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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT4
All Species:
24.85
Human Site:
S252
Identified Species:
54.67
UniProt:
P56705
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56705
NP_110388.2
351
39052
S252
E
P
R
R
V
G
S
S
R
A
L
V
P
R
N
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
G250
Q
V
V
M
N
Q
D
G
T
G
F
T
V
A
N
Rhesus Macaque
Macaca mulatta
XP_001101962
380
42363
R281
A
A
M
R
L
N
S
R
G
K
L
V
Q
V
N
Dog
Lupus familis
XP_855190
438
47738
S339
E
P
R
R
V
G
S
S
R
A
L
V
P
R
N
Cat
Felis silvestris
Mouse
Mus musculus
P22724
351
39031
S252
E
P
R
R
V
G
S
S
R
A
L
V
P
R
N
Rat
Rattus norvegicus
Q9QXQ5
351
39025
S252
E
P
R
R
V
G
S
S
R
A
L
V
P
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
G251
Q
V
V
M
N
Q
D
G
T
G
F
T
V
A
N
Chicken
Gallus gallus
P49337
351
38945
T252
E
Q
S
E
I
G
S
T
K
V
L
V
P
K
N
Frog
Xenopus laevis
P49338
351
39148
T252
E
Q
K
K
I
G
S
T
K
V
L
V
P
K
N
Zebra Danio
Brachydanio rerio
P47793
352
39413
T252
E
L
R
K
V
G
T
T
K
V
L
V
P
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786346
623
69928
R525
Q
S
L
K
I
G
S
R
Q
Q
L
V
P
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
46.5
78.5
N.A.
98.8
98.2
N.A.
48.7
85.4
85.4
82.3
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
65
63.1
79.2
N.A.
99.7
99.1
N.A.
65
92.8
94
93.4
N.A.
N.A.
N.A.
N.A.
45.2
P-Site Identity:
100
6.6
33.3
100
N.A.
100
100
N.A.
6.6
46.6
46.6
60
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
13.3
40
100
N.A.
100
100
N.A.
13.3
73.3
86.6
86.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
37
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% D
% Glu:
64
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% F
% Gly:
0
0
0
0
0
73
0
19
10
19
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
28
0
0
0
0
28
10
0
0
0
19
0
% K
% Leu:
0
10
10
0
10
0
0
0
0
0
82
0
0
0
0
% L
% Met:
0
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
19
10
0
0
0
0
0
0
0
0
100
% N
% Pro:
0
37
0
0
0
0
0
0
0
0
0
0
73
0
0
% P
% Gln:
28
19
0
0
0
19
0
0
10
10
0
0
10
0
0
% Q
% Arg:
0
0
46
46
0
0
0
19
37
0
0
0
0
55
0
% R
% Ser:
0
10
10
0
0
0
73
37
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
28
19
0
0
19
0
0
0
% T
% Val:
0
19
19
0
46
0
0
0
0
28
0
82
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _