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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT7B
All Species:
36.36
Human Site:
S274
Identified Species:
80
UniProt:
P56706
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56706
NP_478679.1
349
39327
S274
D
L
V
Y
I
E
K
S
P
N
Y
C
E
E
D
Chimpanzee
Pan troglodytes
XP_513634
460
51523
S374
D
L
V
Y
F
D
N
S
P
D
Y
C
V
L
D
Rhesus Macaque
Macaca mulatta
XP_001110372
349
39282
S274
D
L
V
Y
I
E
K
S
P
N
Y
C
E
E
D
Dog
Lupus familis
XP_538327
349
39341
S274
D
L
V
Y
I
E
K
S
P
N
Y
C
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P28047
349
39284
S274
D
L
V
Y
I
E
K
S
P
N
Y
C
E
E
D
Rat
Rattus norvegicus
Q9QXQ5
351
39025
S276
D
L
V
Y
L
E
P
S
P
D
F
C
E
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
S275
D
L
V
Y
F
E
N
S
P
D
Y
C
I
K
D
Chicken
Gallus gallus
Q3L254
349
39512
S274
D
L
V
Y
I
E
K
S
P
N
Y
C
E
E
D
Frog
Xenopus laevis
P87387
351
40101
S265
D
L
V
Y
F
E
N
S
P
D
Y
C
V
M
D
Zebra Danio
Brachydanio rerio
P47793
352
39413
C280
L
D
P
S
P
D
F
C
E
H
D
P
R
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787051
370
41758
S295
H
L
V
F
L
H
R
S
P
N
Y
C
E
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
99.7
99.1
N.A.
99.1
47.2
N.A.
45.4
95.4
48.1
47.1
N.A.
N.A.
N.A.
N.A.
59.1
Protein Similarity:
100
52.8
99.7
100
N.A.
100
64.3
N.A.
62.8
99.1
64.3
65.6
N.A.
N.A.
N.A.
N.A.
72.9
P-Site Identity:
100
60
100
100
N.A.
100
66.6
N.A.
66.6
100
66.6
0
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
73.3
100
100
N.A.
100
93.3
N.A.
80
100
73.3
13.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
91
0
0
0
% C
% Asp:
82
10
0
0
0
19
0
0
0
37
10
0
0
0
91
% D
% Glu:
0
0
0
0
0
73
0
0
10
0
0
0
64
46
0
% E
% Phe:
0
0
0
10
28
0
10
0
0
0
10
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
46
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
46
0
0
0
0
0
0
10
0
% K
% Leu:
10
91
0
0
19
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
28
0
0
55
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
0
10
0
91
0
0
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
10
0
0
0
91
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
91
0
0
0
0
0
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
82
0
0
0
0
0
0
82
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _