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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT7B
All Species:
22.73
Human Site:
T250
Identified Species:
50
UniProt:
P56706
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56706
NP_478679.1
349
39327
T250
A
S
R
L
R
Q
P
T
F
L
R
I
K
Q
L
Chimpanzee
Pan troglodytes
XP_513634
460
51523
G350
Q
V
M
A
T
Q
D
G
A
N
F
T
A
A
R
Rhesus Macaque
Macaca mulatta
XP_001110372
349
39282
T250
A
S
R
L
R
Q
P
T
F
L
R
I
K
Q
L
Dog
Lupus familis
XP_538327
349
39341
T250
A
S
R
L
R
Q
P
T
F
L
R
I
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P28047
349
39284
T250
A
S
R
L
R
Q
P
T
F
L
R
I
K
Q
L
Rat
Rattus norvegicus
Q9QXQ5
351
39025
S252
E
P
R
R
V
G
S
S
R
A
L
V
P
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
G251
Q
V
V
M
N
Q
D
G
T
G
F
T
V
A
N
Chicken
Gallus gallus
Q3L254
349
39512
T250
A
S
R
L
R
Q
P
T
F
L
K
I
K
Q
I
Frog
Xenopus laevis
P87387
351
40101
G241
Q
V
T
M
N
Q
D
G
S
G
F
A
V
A
N
Zebra Danio
Brachydanio rerio
P47793
352
39413
V256
V
G
T
T
K
V
L
V
P
R
N
S
Q
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787051
370
41758
T271
A
K
R
T
R
R
P
T
F
L
K
V
K
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
99.7
99.1
N.A.
99.1
47.2
N.A.
45.4
95.4
48.1
47.1
N.A.
N.A.
N.A.
N.A.
59.1
Protein Similarity:
100
52.8
99.7
100
N.A.
100
64.3
N.A.
62.8
99.1
64.3
65.6
N.A.
N.A.
N.A.
N.A.
72.9
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
6.6
86.6
6.6
0
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
26.6
N.A.
13.3
100
13.3
13.3
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
0
0
10
0
0
0
0
10
10
0
10
10
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
28
0
0
0
0
0
0
10
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
55
0
28
0
0
10
0
% F
% Gly:
0
10
0
0
0
10
0
28
0
19
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
46
0
0
10
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
19
0
55
0
10
% K
% Leu:
0
0
0
46
0
0
10
0
0
55
10
0
0
0
37
% L
% Met:
0
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
10
10
0
0
0
28
% N
% Pro:
0
10
0
0
0
0
55
0
10
0
0
0
10
0
0
% P
% Gln:
28
0
0
0
0
73
0
0
0
0
0
0
10
46
0
% Q
% Arg:
0
0
64
10
55
10
0
0
10
10
37
0
0
10
10
% R
% Ser:
0
46
0
0
0
0
10
10
10
0
0
10
0
0
10
% S
% Thr:
0
0
19
19
10
0
0
55
10
0
0
19
0
0
0
% T
% Val:
10
28
10
0
10
10
0
10
0
0
0
19
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _