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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS12
All Species:
13.03
Human Site:
Y798
Identified Species:
35.83
UniProt:
P56730
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56730
NP_003610.1
875
97067
Y798
K
R
F
C
E
E
R
Y
K
G
R
F
T
G
R
Chimpanzee
Pan troglodytes
Q5G271
875
97141
Y798
K
R
F
C
E
E
R
Y
K
R
R
F
T
G
R
Rhesus Macaque
Macaca mulatta
Q5G267
875
97168
Y798
K
R
F
C
E
E
R
Y
K
G
R
F
T
G
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08762
761
84100
L687
C
K
E
R
Y
K
G
L
F
T
G
R
M
L
C
Rat
Rattus norvegicus
Q8CIZ5
1418
155701
S1323
C
R
A
N
D
V
S
S
R
C
Y
R
G
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508784
743
82001
R669
C
E
E
R
Y
K
S
R
F
T
G
R
M
L
C
Chicken
Gallus gallus
XP_420637
740
81809
R666
C
E
E
R
Y
K
R
R
F
T
G
R
M
L
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920299
823
90091
Y746
K
R
Q
C
E
Q
R
Y
S
E
Q
F
T
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16264
532
57801
E458
G
I
T
C
S
G
V
E
N
E
T
L
S
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.5
N.A.
N.A.
72.2
22.5
N.A.
72
70.8
N.A.
57.3
N.A.
N.A.
N.A.
N.A.
23.5
Protein Similarity:
100
99.7
98.1
N.A.
N.A.
77.8
31.8
N.A.
78.5
76.6
N.A.
71
N.A.
N.A.
N.A.
N.A.
34
P-Site Identity:
100
93.3
100
N.A.
N.A.
0
6.6
N.A.
0
6.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
100
N.A.
N.A.
13.3
20
N.A.
6.6
13.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
45
0
0
56
0
0
0
0
0
12
0
0
0
12
45
% C
% Asp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
23
34
0
45
34
0
12
0
23
0
0
0
0
0
% E
% Phe:
0
0
34
0
0
0
0
0
34
0
0
45
0
0
0
% F
% Gly:
12
0
0
0
0
12
12
0
0
23
34
0
12
34
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
45
12
0
0
0
34
0
0
34
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
0
12
0
34
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
12
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
12
0
0
0
0
12
0
0
12
0
% Q
% Arg:
0
56
0
34
0
0
56
23
12
12
34
45
0
0
45
% R
% Ser:
0
0
0
0
12
0
23
12
12
0
0
0
12
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
34
12
0
45
0
0
% T
% Val:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
0
0
45
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _