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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN15
All Species:
4.55
Human Site:
S111
Identified Species:
12.5
UniProt:
P56746
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56746
NP_055158.1
228
24356
S111
N
I
G
G
L
E
L
S
R
K
A
K
L
A
A
Chimpanzee
Pan troglodytes
XP_519278
194
20690
A80
G
Y
I
Q
A
C
R
A
L
M
I
T
A
I
L
Rhesus Macaque
Macaca mulatta
XP_001086030
228
24440
K111
T
K
V
G
G
S
D
K
A
K
A
K
I
A
C
Dog
Lupus familis
XP_850281
179
19038
F65
G
V
Y
S
C
R
E
F
P
S
L
L
A
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S5
227
24262
S111
N
V
G
N
M
D
L
S
K
K
A
K
L
L
A
Rat
Rattus norvegicus
Q5QT56
224
23297
S110
K
C
T
R
V
G
D
S
N
P
T
A
K
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507610
262
28211
R111
L
V
A
Q
H
N
P
R
L
K
A
N
L
A
A
Chicken
Gallus gallus
XP_416985
228
24353
N112
K
I
G
G
S
D
Q
N
K
A
R
I
A
C
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9YH92
215
22846
G101
G
L
G
V
A
S
M
G
M
K
C
T
N
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
42.9
60.9
N.A.
78
36.8
N.A.
56.8
44.7
N.A.
35
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.6
60.9
68.8
N.A.
86.8
60.9
N.A.
67.5
60
N.A.
53.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
33.3
0
N.A.
60
6.6
N.A.
33.3
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
40
13.3
N.A.
86.6
13.3
N.A.
40
40
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
23
0
0
12
12
12
45
12
34
34
34
% A
% Cys:
0
12
0
0
12
12
0
0
0
0
12
0
0
23
12
% C
% Asp:
0
0
0
0
0
23
23
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
34
0
45
34
12
12
0
12
0
0
0
0
0
12
12
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
12
0
0
0
0
0
0
0
12
12
12
12
0
% I
% Lys:
23
12
0
0
0
0
0
12
23
56
0
34
12
0
0
% K
% Leu:
12
12
0
0
12
0
23
0
23
0
12
12
34
23
23
% L
% Met:
0
0
0
0
12
0
12
0
12
12
0
0
0
0
0
% M
% Asn:
23
0
0
12
0
12
0
12
12
0
0
12
12
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
12
12
0
0
0
0
0
% P
% Gln:
0
0
0
23
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
12
12
12
12
0
12
0
0
0
12
% R
% Ser:
0
0
0
12
12
23
0
34
0
12
0
0
0
0
12
% S
% Thr:
12
0
12
0
0
0
0
0
0
0
12
23
0
0
0
% T
% Val:
0
34
12
12
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _