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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN6
All Species:
11.82
Human Site:
T202
Identified Species:
32.5
UniProt:
P56747
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56747
NP_067018.2
220
23292
T202
H
Y
M
A
R
Y
S
T
S
A
P
A
I
S
R
Chimpanzee
Pan troglodytes
XP_523276
220
23303
T202
H
Y
M
A
R
Y
S
T
S
A
P
A
I
S
R
Rhesus Macaque
Macaca mulatta
XP_001088715
220
23301
T202
H
Y
M
A
R
Y
S
T
S
A
P
A
I
S
R
Dog
Lupus familis
XP_547168
221
23303
A202
H
Y
M
A
R
Y
S
A
S
A
A
H
A
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z262
219
23369
T202
H
Y
M
A
C
Y
S
T
S
V
P
H
S
R
G
Rat
Rattus norvegicus
Q63400
219
23296
R201
K
I
L
Y
S
A
P
R
S
T
G
P
G
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989533
214
23072
P193
P
K
D
E
R
Y
A
P
S
K
V
A
Y
S
A
Frog
Xenopus laevis
NP_001082330
213
22895
A195
R
E
D
N
H
Y
S
A
Q
Y
T
A
A
S
Q
Zebra Danio
Brachydanio rerio
Q9YH91
208
22187
E189
C
C
Q
C
P
K
N
E
G
R
A
Y
S
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
88.6
N.A.
87.7
58.1
N.A.
N.A.
61.8
65.9
60.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
100
93.6
N.A.
94
77.7
N.A.
N.A.
81.3
85
79.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
60
6.6
N.A.
N.A.
33.3
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
60
20
N.A.
N.A.
40
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
56
0
12
12
23
0
45
23
56
23
0
12
% A
% Cys:
12
12
0
12
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
12
0
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
12
0
12
0
23
% G
% His:
56
0
0
0
12
0
0
0
0
0
0
23
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
34
0
0
% I
% Lys:
12
12
0
0
0
12
0
0
0
12
0
0
0
0
12
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
12
0
12
12
0
0
45
12
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
12
% Q
% Arg:
12
0
0
0
56
0
0
12
0
12
0
0
0
12
34
% R
% Ser:
0
0
0
0
12
0
67
0
78
0
0
0
23
56
12
% S
% Thr:
0
0
0
0
0
0
0
45
0
12
12
0
0
23
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
12
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
56
0
12
0
78
0
0
0
12
0
12
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _