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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN12
All Species:
23.64
Human Site:
Y75
Identified Species:
86.67
UniProt:
P56749
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56749
NP_036261.1
244
27110
Y75
L
M
Y
D
T
T
W
Y
S
S
V
D
Q
L
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849839
244
27077
Y75
L
M
Y
D
T
T
W
Y
S
S
V
D
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET43
244
26976
Y75
L
M
Y
D
R
T
W
Y
L
S
V
D
Q
L
D
Rat
Rattus norvegicus
NP_001094283
244
27002
Y75
L
M
Y
D
R
T
W
Y
L
S
V
D
Q
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234158
245
27202
Y75
V
I
Y
D
P
Q
W
Y
T
A
V
D
Q
L
D
Frog
Xenopus laevis
NP_001088979
245
27343
Y75
M
M
Y
D
M
E
W
Y
A
S
V
D
Q
L
D
Zebra Danio
Brachydanio rerio
NP_571848
341
37453
Y75
Y
Y
F
D
S
D
W
Y
A
K
V
D
Q
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.1
N.A.
91.3
92.6
N.A.
N.A.
77.5
68.1
40.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
96.3
97.1
N.A.
N.A.
89.8
83.2
53
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
N.A.
60
73.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
N.A.
86.6
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
29
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
0
15
0
0
0
0
0
100
0
0
100
% D
% Glu:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% K
% Leu:
58
0
0
0
0
0
0
0
29
0
0
0
0
100
0
% L
% Met:
15
72
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
0
0
0
0
0
100
0
0
% Q
% Arg:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
15
0
0
0
29
72
0
0
0
0
0
% S
% Thr:
0
0
0
0
29
58
0
0
15
0
0
0
0
0
0
% T
% Val:
15
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% W
% Tyr:
15
15
86
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _