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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN17
All Species:
20.3
Human Site:
Y117
Identified Species:
55.83
UniProt:
P56750
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56750
NP_036263.1
224
24603
Y117
S
N
E
R
A
K
A
Y
L
L
G
T
S
G
V
Chimpanzee
Pan troglodytes
XP_531531
224
24498
Y117
S
N
E
R
A
K
A
Y
L
L
G
T
S
G
V
Rhesus Macaque
Macaca mulatta
XP_001100305
224
24604
Y117
S
N
E
R
A
K
A
Y
L
L
G
T
S
G
V
Dog
Lupus familis
XP_544844
224
24608
Y117
S
N
E
R
A
K
A
Y
L
L
G
T
S
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXA6
224
24635
Y117
S
S
E
R
V
K
A
Y
L
L
G
T
S
G
V
Rat
Rattus norvegicus
Q63400
219
23296
K115
Q
D
E
T
A
K
A
K
I
T
I
V
A
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425544
224
24558
Y117
S
G
W
P
T
K
G
Y
I
L
V
A
A
G
L
Frog
Xenopus laevis
NP_001087400
213
22866
K115
Q
D
E
S
A
K
A
K
I
M
I
V
S
G
V
Zebra Danio
Brachydanio rerio
Q9YH90
209
22072
L115
A
D
N
S
A
K
A
L
V
A
T
T
G
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
95
91
N.A.
81.6
43.7
N.A.
N.A.
51.3
46.4
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
96.4
95.5
N.A.
91.9
60.7
N.A.
N.A.
65.1
66.5
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
40
N.A.
N.A.
33.3
46.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
60
N.A.
N.A.
53.3
66.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
78
0
89
0
0
12
0
12
23
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
12
0
0
0
56
0
12
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
34
0
23
0
0
0
0
% I
% Lys:
0
0
0
0
0
100
0
23
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
56
67
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
45
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
56
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
67
12
0
23
0
0
0
0
0
0
0
0
67
0
0
% S
% Thr:
0
0
0
12
12
0
0
0
0
12
12
67
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
12
0
12
23
0
0
89
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _