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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN20
All Species:
4.24
Human Site:
S203
Identified Species:
10.37
UniProt:
P56880
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56880
NP_001001346.1
219
23515
S203
P
P
T
Q
Q
P
I
S
N
T
Q
L
E
N
N
Chimpanzee
Pan troglodytes
XP_511974
211
22381
R196
N
E
S
K
A
G
Y
R
A
P
R
S
Y
P
K
Rhesus Macaque
Macaca mulatta
XP_001094900
219
23510
S203
P
P
M
Q
Q
P
I
S
N
T
Q
L
E
N
N
Dog
Lupus familis
XP_850752
219
23395
P203
P
P
K
Q
Q
H
I
P
A
T
Q
L
E
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET38
224
23325
P203
P
Q
P
Y
R
S
G
P
S
T
A
A
R
E
P
Rat
Rattus norvegicus
Q5QT56
224
23297
P203
P
Q
P
Y
R
S
G
P
S
T
A
A
R
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512437
235
24858
A203
L
P
P
R
G
P
P
A
A
P
P
Y
L
P
P
Chicken
Gallus gallus
XP_001232003
219
23706
P203
P
P
K
Q
Q
H
L
P
S
T
M
Q
E
S
S
Frog
Xenopus laevis
NP_001086045
236
25557
R203
T
P
Q
R
R
Y
P
R
K
T
P
T
S
R
S
Zebra Danio
Brachydanio rerio
Q9YH92
215
22846
R200
P
N
Y
P
K
S
S
R
P
V
K
S
S
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.8
97.2
88.5
N.A.
34.3
33.9
N.A.
40
67.1
41.5
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.1
97.7
92.6
N.A.
53.5
53.5
N.A.
57.8
81.7
58
57.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
66.6
N.A.
13.3
13.3
N.A.
13.3
40
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
66.6
N.A.
26.6
26.6
N.A.
26.6
66.6
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
30
0
20
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
40
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
20
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
10
10
0
0
0
10
0
10
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
10
0
0
0
0
30
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
20
0
0
0
0
20
30
% N
% Pro:
70
60
30
10
0
30
20
40
10
20
20
0
0
20
40
% P
% Gln:
0
20
10
40
40
0
0
0
0
0
30
10
0
0
0
% Q
% Arg:
0
0
0
20
30
0
0
30
0
0
10
0
20
20
0
% R
% Ser:
0
0
10
0
0
30
10
20
30
0
0
20
20
10
20
% S
% Thr:
10
0
10
0
0
0
0
0
0
70
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
20
0
10
10
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _