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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B7
All Species:
5.45
Human Site:
S278
Identified Species:
20
UniProt:
P56937
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56937
NP_057455.1
341
38206
S278
L
F
H
Q
K
P
E
S
L
N
P
L
I
K
Y
Chimpanzee
Pan troglodytes
XP_001174381
341
38215
S278
L
F
H
Q
K
P
E
S
L
N
P
L
I
K
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851698
330
37025
A267
T
P
Y
N
G
T
E
A
L
V
W
L
F
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
O88736
334
37298
F272
A
E
A
L
V
W
L
F
H
Q
K
P
E
S
L
Rat
Rattus norvegicus
Q62904
334
37353
F272
A
E
A
L
V
W
L
F
H
Q
K
P
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089657
329
36837
A267
S
T
Y
N
G
A
E
A
L
M
W
L
F
K
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793145
355
39612
S290
E
A
L
V
W
L
F
S
T
S
P
E
T
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
83.8
N.A.
77.1
80.3
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
100
N.A.
89.7
N.A.
87.9
89.4
N.A.
N.A.
N.A.
82.1
N.A.
N.A.
N.A.
N.A.
N.A.
61.6
P-Site Identity:
100
100
N.A.
20
N.A.
0
0
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
33.3
N.A.
0
0
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
15
29
0
0
15
0
29
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
15
29
0
0
0
0
58
0
0
0
0
15
29
0
0
% E
% Phe:
0
29
0
0
0
0
15
29
0
0
0
0
29
0
0
% F
% Gly:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
29
0
0
0
0
0
29
0
0
0
0
15
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% I
% Lys:
0
0
0
0
29
0
0
0
0
0
29
0
0
43
15
% K
% Leu:
29
0
15
29
0
15
29
0
58
0
0
58
0
0
29
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
29
0
0
0
0
0
29
0
0
0
0
0
% N
% Pro:
0
15
0
0
0
29
0
0
0
0
43
29
0
0
0
% P
% Gln:
0
0
0
29
0
0
0
0
0
29
0
0
0
0
29
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
0
0
0
0
0
43
0
15
0
0
0
29
0
% S
% Thr:
15
15
0
0
0
15
0
0
15
0
0
0
15
15
0
% T
% Val:
0
0
0
15
29
0
0
0
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
15
29
0
0
0
0
29
0
0
0
0
% W
% Tyr:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _