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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B7
All Species:
4.55
Human Site:
T258
Identified Species:
16.67
UniProt:
P56937
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56937
NP_057455.1
341
38206
T258
R
F
F
A
N
A
F
T
L
T
P
Y
N
G
T
Chimpanzee
Pan troglodytes
XP_001174381
341
38215
T258
R
F
F
A
N
A
F
T
L
T
P
Y
N
G
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851698
330
37025
I247
W
T
L
L
L
P
I
I
W
L
L
R
F
F
A
Cat
Felis silvestris
Mouse
Mus musculus
O88736
334
37298
F252
P
I
M
W
L
L
R
F
F
V
N
A
L
T
V
Rat
Rattus norvegicus
Q62904
334
37353
F252
P
V
I
W
L
L
R
F
F
A
H
A
F
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089657
329
36837
M247
W
T
L
I
M
P
I
M
W
L
I
R
I
F
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793145
355
39612
V270
F
H
S
L
F
R
L
V
A
P
R
L
C
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
83.8
N.A.
77.1
80.3
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
100
N.A.
89.7
N.A.
87.9
89.4
N.A.
N.A.
N.A.
82.1
N.A.
N.A.
N.A.
N.A.
N.A.
61.6
P-Site Identity:
100
100
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
29
0
29
0
0
15
15
0
29
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
15
29
29
0
15
0
29
29
29
0
0
0
29
29
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
0
% G
% His:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% H
% Ile:
0
15
15
15
0
0
29
15
0
0
15
0
15
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
29
29
43
29
15
0
29
29
15
15
15
0
0
% L
% Met:
0
0
15
0
15
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
29
0
0
0
0
0
15
0
29
0
0
% N
% Pro:
29
0
0
0
0
29
0
0
0
15
29
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
29
0
0
0
0
15
29
0
0
0
15
29
0
0
0
% R
% Ser:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
29
0
0
0
0
0
29
0
29
0
0
0
29
58
% T
% Val:
0
15
0
0
0
0
0
15
0
15
0
0
0
0
29
% V
% Trp:
29
0
0
29
0
0
0
0
29
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
29
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _