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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B7
All Species:
4.55
Human Site:
Y313
Identified Species:
16.67
UniProt:
P56937
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56937
NP_057455.1
341
38206
Y313
E
D
T
A
E
K
F
Y
Q
K
L
L
E
L
E
Chimpanzee
Pan troglodytes
XP_001174381
341
38215
Y313
E
D
T
A
E
K
F
Y
Q
K
L
L
E
L
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851698
330
37025
M302
N
Y
V
A
T
Q
K
M
D
L
D
E
D
T
A
Cat
Felis silvestris
Mouse
Mus musculus
O88736
334
37298
D307
Q
K
M
D
I
D
E
D
T
A
E
K
F
Y
E
Rat
Rattus norvegicus
Q62904
334
37353
D307
Q
K
M
D
V
D
E
D
T
A
E
K
F
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089657
329
36837
M302
N
Y
V
N
L
T
K
M
D
V
E
E
E
S
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793145
355
39612
H325
K
L
D
M
N
P
D
H
A
E
L
L
Y
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
83.8
N.A.
77.1
80.3
N.A.
N.A.
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
100
N.A.
89.7
N.A.
87.9
89.4
N.A.
N.A.
N.A.
82.1
N.A.
N.A.
N.A.
N.A.
N.A.
61.6
P-Site Identity:
100
100
N.A.
6.6
N.A.
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
43
0
0
0
0
15
29
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
29
15
29
0
29
15
29
29
0
15
0
15
0
0
% D
% Glu:
29
0
0
0
29
0
29
0
0
15
43
29
43
0
43
% E
% Phe:
0
0
0
0
0
0
29
0
0
0
0
0
29
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
15
29
0
0
0
29
29
0
0
29
0
29
0
15
29
% K
% Leu:
0
15
0
0
15
0
0
0
0
15
43
43
0
29
0
% L
% Met:
0
0
29
15
0
0
0
29
0
0
0
0
0
0
0
% M
% Asn:
29
0
0
15
15
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% P
% Gln:
29
0
0
0
0
15
0
0
29
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% S
% Thr:
0
0
29
0
15
15
0
0
29
0
0
0
0
15
0
% T
% Val:
0
0
29
0
15
0
0
0
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
29
0
0
0
0
0
29
0
0
0
0
15
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _