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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX17
All Species:
5.76
Human Site:
S149
Identified Species:
11.52
UniProt:
P56962
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56962
NP_060389.2
302
33403
S149
H
T
T
E
A
E
A
S
S
Q
S
L
T
Q
I
Chimpanzee
Pan troglodytes
XP_001159638
140
16506
Q18
R
R
L
E
P
A
I
Q
K
F
I
K
I
V
I
Rhesus Macaque
Macaca mulatta
XP_001112469
302
33397
S149
H
T
T
E
A
E
A
S
S
Q
S
L
T
Q
I
Dog
Lupus familis
XP_538752
302
33572
D149
H
T
A
E
A
E
A
D
P
Q
T
M
T
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0I4
301
33203
A148
H
T
G
E
A
E
A
A
S
Q
S
L
T
Q
I
Rat
Rattus norvegicus
Q9Z158
301
33164
A148
H
T
G
E
A
E
A
A
S
Q
S
L
T
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506027
303
33726
P150
T
P
E
A
E
E
Y
P
Y
G
L
M
Q
M
E
Chicken
Gallus gallus
NP_001026180
302
33255
S149
I
T
E
A
K
D
G
S
Q
S
L
I
Q
M
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007450
291
31752
G139
E
D
D
T
G
V
S
G
S
P
V
T
Q
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523926
301
33776
P143
L
P
A
H
R
H
M
P
Q
L
Q
L
N
F
Q
Honey Bee
Apis mellifera
XP_394196
313
35762
D147
Q
A
N
S
H
P
L
D
N
T
Y
I
Q
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781096
348
38420
D192
V
H
H
P
L
L
H
D
E
Q
Q
Q
Q
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
99.6
95.6
N.A.
92.3
90.7
N.A.
78.2
75.1
N.A.
53.3
N.A.
33.1
27.7
N.A.
37.6
Protein Similarity:
100
46.3
99.6
97.6
N.A.
94.6
95
N.A.
88.1
87.4
N.A.
71.8
N.A.
53.3
46.9
N.A.
54.6
P-Site Identity:
100
13.3
100
60
N.A.
86.6
86.6
N.A.
6.6
13.3
N.A.
6.6
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
13.3
100
80
N.A.
93.3
93.3
N.A.
13.3
26.6
N.A.
13.3
N.A.
6.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
17
42
9
42
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
9
0
0
9
0
25
0
0
0
0
0
0
0
% D
% Glu:
9
0
17
50
9
50
0
0
9
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% F
% Gly:
0
0
17
0
9
0
9
9
0
9
0
0
0
0
0
% G
% His:
42
9
9
9
9
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
0
0
0
9
17
9
0
42
% I
% Lys:
0
0
0
0
9
0
0
0
9
0
0
9
0
0
0
% K
% Leu:
9
0
9
0
9
9
9
0
0
9
17
42
0
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
17
0
17
0
% M
% Asn:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
17
0
9
9
9
0
17
9
9
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
9
17
50
17
9
42
50
34
% Q
% Arg:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
9
25
42
9
34
0
0
0
0
% S
% Thr:
9
50
17
9
0
0
0
0
0
9
9
9
42
9
0
% T
% Val:
9
0
0
0
0
9
0
0
0
0
9
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _