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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX17 All Species: 30.61
Human Site: T287 Identified Species: 61.21
UniProt: P56962 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56962 NP_060389.2 302 33403 T287 Q K M M E K L T S S C P D L P
Chimpanzee Pan troglodytes XP_001159638 140 16506 L126 Q F N D E E T L L Q P P L T R
Rhesus Macaque Macaca mulatta XP_001112469 302 33397 T287 Q K M M E K L T S S C P D L P
Dog Lupus familis XP_538752 302 33572 T287 Q K M M E K L T S S C P D L P
Cat Felis silvestris
Mouse Mus musculus Q9D0I4 301 33203 T286 Q K M M E K L T S S C P D L P
Rat Rattus norvegicus Q9Z158 301 33164 T286 Q K M M E K L T S S C P D L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506027 303 33726 S288 Q K M M E E L S S S C P D L P
Chicken Gallus gallus NP_001026180 302 33255 S287 Q K Q I E Q V S C S C P E L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007450 291 31752 L277 K E R I D L Q L Q E L H S N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523926 301 33776 E280 N V M H G N I E E E Q V E P D
Honey Bee Apis mellifera XP_394196 313 35762 S299 E Q K P I Q R S S S L P E N L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781096 348 38420 T333 Q M E M S I L T N G T L E G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.3 99.6 95.6 N.A. 92.3 90.7 N.A. 78.2 75.1 N.A. 53.3 N.A. 33.1 27.7 N.A. 37.6
Protein Similarity: 100 46.3 99.6 97.6 N.A. 94.6 95 N.A. 88.1 87.4 N.A. 71.8 N.A. 53.3 46.9 N.A. 54.6
P-Site Identity: 100 20 100 100 N.A. 100 100 N.A. 86.6 46.6 N.A. 0 N.A. 6.6 20 N.A. 26.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 80 N.A. 26.6 N.A. 20 53.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 59 0 0 0 0 % C
% Asp: 0 0 0 9 9 0 0 0 0 0 0 0 50 0 9 % D
% Glu: 9 9 9 0 67 17 0 9 9 17 0 0 34 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 9 0 0 0 9 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 17 9 9 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 59 9 0 0 42 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 9 59 17 9 0 17 9 9 59 9 % L
% Met: 0 9 59 59 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 9 0 0 9 0 0 0 0 17 9 % N
% Pro: 0 0 0 9 0 0 0 0 0 0 9 75 0 9 50 % P
% Gln: 75 9 9 0 0 17 9 0 9 9 9 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 0 0 9 0 0 25 59 67 0 0 9 0 17 % S
% Thr: 0 0 0 0 0 0 9 50 0 0 9 0 0 9 0 % T
% Val: 0 9 0 0 0 0 9 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _