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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NRG3
All Species:
9.09
Human Site:
Y553
Identified Species:
28.57
UniProt:
P56975
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56975
NP_001010848.2
720
77901
Y553
E
R
P
L
D
L
K
Y
S
S
S
G
L
K
T
Chimpanzee
Pan troglodytes
XP_521696
153
17053
Rhesus Macaque
Macaca mulatta
XP_001087016
370
41438
N206
L
D
L
K
Y
S
S
N
G
L
K
T
Q
R
N
Dog
Lupus familis
XP_536405
345
38599
G181
L
D
F
K
Y
S
S
G
G
L
K
T
Q
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
O35181
713
77352
Y546
E
R
P
L
D
L
K
Y
V
S
N
G
L
R
T
Rat
Rattus norvegicus
XP_573873
719
77917
Y552
E
R
P
L
D
L
K
Y
A
S
N
G
L
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426491
432
48285
S268
P
C
H
G
Y
S
S
S
G
L
K
T
P
Q
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47179
1161
118341
E724
T
S
T
S
F
I
A
E
R
T
S
S
L
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.2
50.9
44.5
N.A.
92.2
92.5
N.A.
N.A.
46.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
21.2
51.2
46.2
N.A.
95.4
95.5
N.A.
N.A.
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
0
N.A.
80
80
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
6.6
6.6
N.A.
93.3
100
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
30.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
38
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
38
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
13
0
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
13
0
0
0
13
38
0
0
38
0
0
0
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
25
0
0
38
0
0
0
38
0
0
13
0
% K
% Leu:
25
0
13
38
0
38
0
0
0
38
0
0
50
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
25
0
0
0
38
% N
% Pro:
13
0
38
0
0
0
0
0
0
0
0
0
13
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
25
25
0
% Q
% Arg:
0
38
0
0
0
0
0
0
13
0
0
0
0
38
0
% R
% Ser:
0
13
0
13
0
38
38
13
13
38
25
13
0
0
0
% S
% Thr:
13
0
13
0
0
0
0
0
0
13
0
38
0
0
38
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
38
0
0
38
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _