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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUNK
All Species:
13.33
Human Site:
S421
Identified Species:
20.95
UniProt:
P57058
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57058
NP_055401.1
714
79686
S421
P
K
E
S
Y
E
A
S
L
D
T
W
T
R
D
Chimpanzee
Pan troglodytes
Q68UT7
714
79665
S421
P
K
E
S
Y
E
A
S
L
D
T
W
T
R
D
Rhesus Macaque
Macaca mulatta
XP_001115547
734
82154
V401
A
P
S
P
S
H
K
V
Q
R
S
V
S
A
N
Dog
Lupus familis
XP_544857
756
84391
S463
T
K
E
P
Y
E
A
S
L
D
T
W
T
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O88866
714
79585
S421
T
K
E
P
Y
E
A
S
L
D
T
W
T
R
D
Rat
Rattus norvegicus
O08679
722
80853
Q405
S
V
S
A
N
P
K
Q
R
R
S
S
D
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513072
722
82227
A425
D
P
D
A
G
T
P
A
T
Q
R
I
E
D
T
Chicken
Gallus gallus
Q9IA88
798
88848
T380
E
M
P
Q
D
S
L
T
S
E
T
L
R
S
S
Frog
Xenopus laevis
Q5XHI9
691
78470
E412
K
M
N
K
N
S
Y
E
E
R
R
S
K
D
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P479
P
G
F
P
R
V
A
P
Q
A
P
F
P
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
E522
P
A
G
V
I
T
R
E
H
V
T
S
S
S
A
Sea Urchin
Strong. purpuratus
XP_794043
962
106011
E440
E
D
V
D
L
D
D
E
A
D
G
V
T
E
A
Poplar Tree
Populus trichocarpa
XP_002306053
515
59069
P249
P
G
A
R
D
L
I
P
R
M
L
V
V
D
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
R246
S
H
L
S
S
E
A
R
D
L
I
P
R
M
L
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
D361
S
T
M
G
Y
E
K
D
E
I
Y
E
S
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
26.1
78.5
N.A.
92.4
24.6
N.A.
35.7
26.6
64.5
23.4
N.A.
N.A.
N.A.
21.5
30
Protein Similarity:
100
99.8
46.4
83
N.A.
95.9
44.7
N.A.
54.5
43.3
76.8
36.6
N.A.
N.A.
N.A.
34.5
45.2
P-Site Identity:
100
100
0
86.6
N.A.
86.6
0
N.A.
0
6.6
0
13.3
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
20
86.6
N.A.
86.6
20
N.A.
20
20
0
20
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
26.3
N.A.
N.A.
25.9
24.9
N.A.
Protein Similarity:
43.2
N.A.
N.A.
43.2
42.7
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
14
0
0
40
7
7
7
0
0
0
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
7
14
7
7
7
7
34
0
0
7
20
27
% D
% Glu:
14
0
27
0
0
40
0
20
14
7
0
7
7
7
7
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
14
7
7
7
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
7
0
0
0
7
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
7
7
7
0
0
0
% I
% Lys:
7
27
0
7
0
0
20
0
0
0
0
0
7
0
0
% K
% Leu:
0
0
7
0
7
7
7
0
27
7
7
7
0
7
20
% L
% Met:
0
14
7
0
0
0
0
0
0
7
0
0
0
7
0
% M
% Asn:
0
0
7
0
14
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
34
14
7
27
0
7
7
14
0
0
7
7
7
7
7
% P
% Gln:
0
0
0
7
0
0
0
7
14
7
0
0
0
7
0
% Q
% Arg:
0
0
0
7
7
0
7
7
14
20
14
0
14
27
0
% R
% Ser:
20
0
14
20
14
14
0
27
7
0
14
20
20
14
7
% S
% Thr:
14
7
0
0
0
14
0
7
7
0
40
0
34
0
7
% T
% Val:
0
7
7
7
0
7
0
7
0
7
0
20
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
27
0
0
0
% W
% Tyr:
0
0
0
0
34
0
7
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _