Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HUNK All Species: 13.64
Human Site: S470 Identified Species: 21.43
UniProt: P57058 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57058 NP_055401.1 714 79686 S470 S H K Q P S G S L M T Q I Q N
Chimpanzee Pan troglodytes Q68UT7 714 79665 S470 S H K Q P S G S L M T Q I Q N
Rhesus Macaque Macaca mulatta XP_001115547 734 82154 K451 E D R E S G R K A S S T A K V
Dog Lupus familis XP_544857 756 84391 S512 S H K Q P S P S L I T Q I Q N
Cat Felis silvestris
Mouse Mus musculus O88866 714 79585 S470 S H K Q P S P S L I T Q L Q S
Rat Rattus norvegicus O08679 722 80853 K443 P E E E T G R K A S S T A K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513072 722 82227 E470 A I I L E N Q E N L P E V S D
Chicken Gallus gallus Q9IA88 798 88848 I433 G L F R N R S I S P S S L L E
Frog Xenopus laevis Q5XHI9 691 78470 T448 H R Q N A C L T P Q G H S N K
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 L668 Y Q Q E Q Q I L H Q Q I Q A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 A572 K H Q Q S S A A P S S G S S S
Sea Urchin Strong. purpuratus XP_794043 962 106011 A497 G S F H F K M A M V I E E E A
Poplar Tree Populus trichocarpa XP_002306053 515 59069 D285 Y L A V P P P D T M Q Q A K K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 V282 H L P R Y L A V S P P D T V E
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 A398 S L I K D M K A N K S V S D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 26.1 78.5 N.A. 92.4 24.6 N.A. 35.7 26.6 64.5 23.4 N.A. N.A. N.A. 21.5 30
Protein Similarity: 100 99.8 46.4 83 N.A. 95.9 44.7 N.A. 54.5 43.3 76.8 36.6 N.A. N.A. N.A. 34.5 45.2
P-Site Identity: 100 100 0 86.6 N.A. 73.3 0 N.A. 0 0 0 0 N.A. N.A. N.A. 20 0
P-Site Similarity: 100 100 26.6 93.3 N.A. 93.3 26.6 N.A. 40 20 13.3 13.3 N.A. N.A. N.A. 46.6 33.3
Percent
Protein Identity: 26.3 N.A. N.A. 25.9 24.9 N.A.
Protein Similarity: 43.2 N.A. N.A. 43.2 42.7 N.A.
P-Site Identity: 20 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 7 0 14 20 14 0 0 0 20 7 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 0 0 7 0 0 0 7 0 7 7 % D
% Glu: 7 7 7 20 7 0 0 7 0 0 0 14 7 7 20 % E
% Phe: 0 0 14 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 0 0 0 14 14 0 0 0 7 7 0 0 0 % G
% His: 14 34 0 7 0 0 0 0 7 0 0 7 0 0 0 % H
% Ile: 0 7 14 0 0 0 7 7 0 14 7 7 20 0 0 % I
% Lys: 7 0 27 7 0 7 7 14 0 7 0 0 0 20 14 % K
% Leu: 0 27 0 7 0 7 7 7 27 7 0 0 14 7 7 % L
% Met: 0 0 0 0 0 7 7 0 7 20 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 7 0 0 14 0 0 0 0 7 20 % N
% Pro: 7 0 7 0 34 7 20 0 14 14 14 0 0 0 0 % P
% Gln: 0 7 20 34 7 7 7 0 0 14 14 34 7 27 0 % Q
% Arg: 0 7 7 14 0 7 14 0 0 0 0 0 0 0 0 % R
% Ser: 34 7 0 0 14 34 7 27 14 20 34 7 20 14 14 % S
% Thr: 0 0 0 0 7 0 0 7 7 0 27 14 7 0 0 % T
% Val: 0 0 0 7 0 0 0 7 0 7 0 7 7 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 14 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _