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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUNK
All Species:
16.97
Human Site:
S490
Identified Species:
26.67
UniProt:
P57058
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57058
NP_055401.1
714
79686
S490
K
D
R
K
A
S
K
S
S
F
P
D
K
D
S
Chimpanzee
Pan troglodytes
Q68UT7
714
79665
S490
K
D
R
K
A
S
K
S
S
F
P
D
K
D
S
Rhesus Macaque
Macaca mulatta
XP_001115547
734
82154
T471
P
G
L
E
R
K
K
T
T
P
T
P
S
T
N
Dog
Lupus familis
XP_544857
756
84391
S532
K
D
R
K
A
P
K
S
G
F
P
D
K
D
A
Cat
Felis silvestris
Mouse
Mus musculus
O88866
714
79585
S490
K
D
R
K
A
S
K
S
G
F
P
D
K
D
S
Rat
Rattus norvegicus
O08679
722
80853
T463
P
G
L
D
R
K
K
T
T
P
T
P
S
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513072
722
82227
N490
L
E
P
L
L
L
M
N
Q
K
S
L
G
E
S
Chicken
Gallus gallus
Q9IA88
798
88848
L453
E
V
R
Q
E
K
E
L
E
D
E
I
K
A
Y
Frog
Xenopus laevis
Q5XHI9
691
78470
R468
R
R
S
S
K
S
E
R
E
S
F
G
G
L
S
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
L688
E
N
Q
P
S
S
H
L
T
Y
Q
L
Q
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
A592
Q
N
D
A
A
A
T
A
A
G
G
T
V
V
M
Sea Urchin
Strong. purpuratus
XP_794043
962
106011
S517
S
P
T
N
V
S
S
S
S
K
A
T
E
T
S
Poplar Tree
Populus trichocarpa
XP_002306053
515
59069
G305
L
Q
E
V
I
K
M
G
F
D
R
N
Q
L
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
V302
N
E
E
I
V
Q
E
V
V
N
M
G
F
D
R
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
Q418
S
Q
S
P
P
T
F
Q
Q
Q
S
K
S
H
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
26.1
78.5
N.A.
92.4
24.6
N.A.
35.7
26.6
64.5
23.4
N.A.
N.A.
N.A.
21.5
30
Protein Similarity:
100
99.8
46.4
83
N.A.
95.9
44.7
N.A.
54.5
43.3
76.8
36.6
N.A.
N.A.
N.A.
34.5
45.2
P-Site Identity:
100
100
6.6
80
N.A.
93.3
6.6
N.A.
6.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
100
33.3
86.6
N.A.
93.3
26.6
N.A.
26.6
33.3
26.6
53.3
N.A.
N.A.
N.A.
40
33.3
Percent
Protein Identity:
26.3
N.A.
N.A.
25.9
24.9
N.A.
Protein Similarity:
43.2
N.A.
N.A.
43.2
42.7
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
34
7
0
7
7
0
7
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
27
7
7
0
0
0
0
0
14
0
27
0
34
0
% D
% Glu:
14
14
14
7
7
0
20
0
14
0
7
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
7
27
7
0
7
0
0
% F
% Gly:
0
14
0
0
0
0
0
7
14
7
7
14
14
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
7
% I
% Lys:
27
0
0
27
7
27
40
0
0
14
0
7
34
0
0
% K
% Leu:
14
0
14
7
7
7
0
14
0
0
0
14
0
14
7
% L
% Met:
0
0
0
0
0
0
14
0
0
0
7
0
0
0
7
% M
% Asn:
7
14
0
7
0
0
0
7
0
7
0
7
0
0
14
% N
% Pro:
14
7
7
14
7
7
0
0
0
14
27
14
0
0
0
% P
% Gln:
7
14
7
7
0
7
0
7
14
7
7
0
14
0
7
% Q
% Arg:
7
7
34
0
14
0
0
7
0
0
7
0
0
7
7
% R
% Ser:
14
0
14
7
7
40
7
34
20
7
14
0
20
0
40
% S
% Thr:
0
0
7
0
0
7
7
14
20
0
14
14
0
20
0
% T
% Val:
0
7
0
7
14
0
0
7
7
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _