KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUNK
All Species:
15.15
Human Site:
S594
Identified Species:
23.81
UniProt:
P57058
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57058
NP_055401.1
714
79686
S594
V
S
L
A
R
R
N
S
S
E
R
T
L
S
P
Chimpanzee
Pan troglodytes
Q68UT7
714
79665
S594
V
S
L
A
R
R
N
S
S
E
R
T
L
S
P
Rhesus Macaque
Macaca mulatta
XP_001115547
734
82154
F589
S
G
S
I
F
S
K
F
T
S
K
F
V
R
R
Dog
Lupus familis
XP_544857
756
84391
P636
G
G
L
A
R
G
N
P
G
E
R
T
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
O88866
714
79585
S594
V
S
L
A
R
R
N
S
S
E
R
T
L
S
Q
Rat
Rattus norvegicus
O08679
722
80853
F581
S
G
S
I
F
S
K
F
T
S
K
F
V
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513072
722
82227
R603
P
Q
L
S
L
L
P
R
L
T
L
A
P
W
R
Chicken
Gallus gallus
Q9IA88
798
88848
M558
V
L
Q
V
Q
G
C
M
G
G
A
S
L
L
P
Frog
Xenopus laevis
Q5XHI9
691
78470
S571
V
S
F
S
P
R
H
S
S
E
R
T
L
S
P
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
L888
S
A
L
Q
Q
A
L
L
S
P
T
P
L
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
A898
G
A
A
A
A
A
S
A
T
N
Q
L
S
G
A
Sea Urchin
Strong. purpuratus
XP_794043
962
106011
S660
E
S
S
A
K
H
G
S
T
N
G
R
V
S
L
Poplar Tree
Populus trichocarpa
XP_002306053
515
59069
T407
A
H
P
R
E
I
M
T
E
V
L
K
A
L
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
R404
L
Q
S
H
A
H
P
R
E
I
M
N
E
V
L
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
G520
S
Y
P
L
D
V
M
G
E
I
Y
I
A
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
26.1
78.5
N.A.
92.4
24.6
N.A.
35.7
26.6
64.5
23.4
N.A.
N.A.
N.A.
21.5
30
Protein Similarity:
100
99.8
46.4
83
N.A.
95.9
44.7
N.A.
54.5
43.3
76.8
36.6
N.A.
N.A.
N.A.
34.5
45.2
P-Site Identity:
100
100
0
66.6
N.A.
93.3
0
N.A.
6.6
20
73.3
20
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
100
20
66.6
N.A.
93.3
20
N.A.
13.3
33.3
86.6
33.3
N.A.
N.A.
N.A.
40
46.6
Percent
Protein Identity:
26.3
N.A.
N.A.
25.9
24.9
N.A.
Protein Similarity:
43.2
N.A.
N.A.
43.2
42.7
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
7
40
14
14
0
7
0
0
7
7
14
0
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
7
0
0
0
20
34
0
0
7
7
0
% E
% Phe:
0
0
7
0
14
0
0
14
0
0
0
14
0
0
0
% F
% Gly:
14
20
0
0
0
14
7
7
14
7
7
0
0
7
0
% G
% His:
0
7
0
7
0
14
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
14
0
7
0
0
0
14
0
7
0
0
0
% I
% Lys:
0
0
0
0
7
0
14
0
0
0
14
7
0
0
7
% K
% Leu:
7
7
40
7
7
7
7
7
7
0
14
7
47
20
14
% L
% Met:
0
0
0
0
0
0
14
7
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
27
0
0
14
0
7
0
0
0
% N
% Pro:
7
0
14
0
7
0
14
7
0
7
0
7
7
0
34
% P
% Gln:
0
14
7
7
14
0
0
0
0
0
7
0
0
0
14
% Q
% Arg:
0
0
0
7
27
27
0
14
0
0
34
7
0
14
20
% R
% Ser:
27
34
27
14
0
14
7
34
34
14
0
7
7
40
0
% S
% Thr:
0
0
0
0
0
0
0
7
27
7
7
34
0
0
0
% T
% Val:
34
0
0
7
0
7
0
0
0
7
0
0
20
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _