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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUNK
All Species:
23.94
Human Site:
T222
Identified Species:
37.62
UniProt:
P57058
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57058
NP_055401.1
714
79686
T222
G
Y
S
D
P
F
S
T
Q
C
G
S
P
A
Y
Chimpanzee
Pan troglodytes
Q68UT7
714
79665
T222
G
Y
S
D
P
F
S
T
Q
C
G
S
P
A
Y
Rhesus Macaque
Macaca mulatta
XP_001115547
734
82154
F209
F
G
N
K
L
D
T
F
C
G
S
P
P
Y
A
Dog
Lupus familis
XP_544857
756
84391
T264
G
H
S
D
P
F
S
T
Q
C
G
S
P
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
O88866
714
79585
T222
G
Y
S
D
P
F
S
T
Q
C
G
S
P
A
Y
Rat
Rattus norvegicus
O08679
722
80853
F209
F
G
N
K
L
D
T
F
C
G
S
P
P
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513072
722
82227
T226
L
S
Q
E
L
L
N
T
Q
C
G
S
P
A
Y
Chicken
Gallus gallus
Q9IA88
798
88848
W182
S
G
E
P
L
S
T
W
C
G
S
P
P
Y
A
Frog
Xenopus laevis
Q5XHI9
691
78470
T215
G
Y
S
D
P
F
S
T
Q
C
G
S
P
A
Y
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
W215
R
G
Q
L
L
K
T
W
C
G
S
P
P
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
F326
L
G
N
K
L
D
T
F
C
G
S
P
P
Y
A
Sea Urchin
Strong. purpuratus
XP_794043
962
106011
T224
G
T
R
D
F
A
G
T
L
C
G
S
P
A
Y
Poplar Tree
Populus trichocarpa
XP_002306053
515
59069
M60
R
K
I
K
N
M
D
M
E
E
K
V
R
R
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
K57
I
L
N
R
R
K
I
K
N
M
E
M
E
E
K
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
H169
I
S
A
V
E
Y
C
H
R
H
K
I
V
H
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
26.1
78.5
N.A.
92.4
24.6
N.A.
35.7
26.6
64.5
23.4
N.A.
N.A.
N.A.
21.5
30
Protein Similarity:
100
99.8
46.4
83
N.A.
95.9
44.7
N.A.
54.5
43.3
76.8
36.6
N.A.
N.A.
N.A.
34.5
45.2
P-Site Identity:
100
100
6.6
93.3
N.A.
100
6.6
N.A.
53.3
6.6
100
6.6
N.A.
N.A.
N.A.
6.6
60
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
66.6
13.3
100
13.3
N.A.
N.A.
N.A.
20
60
Percent
Protein Identity:
26.3
N.A.
N.A.
25.9
24.9
N.A.
Protein Similarity:
43.2
N.A.
N.A.
43.2
42.7
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
0
0
0
0
0
47
34
% A
% Cys:
0
0
0
0
0
0
7
0
34
47
0
0
0
0
0
% C
% Asp:
0
0
0
40
0
20
7
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
7
7
0
0
0
7
7
7
0
7
7
7
% E
% Phe:
14
0
0
0
7
34
0
20
0
0
0
0
0
0
0
% F
% Gly:
40
34
0
0
0
0
7
0
0
34
47
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
7
0
7
0
0
0
7
0
% H
% Ile:
14
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% I
% Lys:
0
7
0
27
0
14
0
7
0
0
14
0
0
0
7
% K
% Leu:
14
7
0
7
40
7
0
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
7
0
7
0
7
0
7
0
0
0
% M
% Asn:
0
0
27
0
7
0
7
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
34
0
0
0
0
0
0
34
80
0
0
% P
% Gln:
0
0
14
0
0
0
0
0
40
0
0
0
0
0
0
% Q
% Arg:
14
0
7
7
7
0
0
0
7
0
0
0
7
7
7
% R
% Ser:
7
14
34
0
0
7
34
0
0
0
34
47
0
0
0
% S
% Thr:
0
7
0
0
0
0
34
47
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% W
% Tyr:
0
27
0
0
0
7
0
0
0
0
0
0
0
34
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _