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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HUNK All Species: 33.03
Human Site: Y103 Identified Species: 51.9
UniProt: P57058 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57058 NP_055401.1 714 79686 Y103 K R A K K D T Y V T K N L R R
Chimpanzee Pan troglodytes Q68UT7 714 79665 Y103 K R A K K D T Y V T K N L R R
Rhesus Macaque Macaca mulatta XP_001115547 734 82154 S92 D K T Q L N S S S L Q K L F R
Dog Lupus familis XP_544857 756 84391 Y145 K R A K K D T Y V T K N L R R
Cat Felis silvestris
Mouse Mus musculus O88866 714 79585 Y103 K R A K K D T Y V T K N L R R
Rat Rattus norvegicus O08679 722 80853 S92 D K T Q L N S S S L Q K L F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513072 722 82227 Y106 R K A Q E D G Y I L E N M R R
Chicken Gallus gallus Q9IA88 798 88848 K69 L D P S N L E K I Y R E V Q I
Frog Xenopus laevis Q5XHI9 691 78470 Y96 K K A K K D T Y V T K N L R R
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 E98 D K T Q L D D E N L K K I F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S210 K T A L N P S S L Q K L F R E
Sea Urchin Strong. purpuratus XP_794043 962 106011 Y105 K A A R E D A Y L H K T L R R
Poplar Tree Populus trichocarpa XP_002306053 515 59069
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 Y73 F G K V K L A Y H T T T G Q K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 26.1 78.5 N.A. 92.4 24.6 N.A. 35.7 26.6 64.5 23.4 N.A. N.A. N.A. 21.5 30
Protein Similarity: 100 99.8 46.4 83 N.A. 95.9 44.7 N.A. 54.5 43.3 76.8 36.6 N.A. N.A. N.A. 34.5 45.2
P-Site Identity: 100 100 13.3 100 N.A. 100 13.3 N.A. 40 0 93.3 20 N.A. N.A. N.A. 26.6 53.3
P-Site Similarity: 100 100 46.6 100 N.A. 100 46.6 N.A. 86.6 26.6 100 40 N.A. N.A. N.A. 40 73.3
Percent
Protein Identity: 26.3 N.A. N.A. 25.9 24.9 N.A.
Protein Similarity: 43.2 N.A. N.A. 43.2 42.7 N.A.
P-Site Identity: 0 N.A. N.A. 0 20 N.A.
P-Site Similarity: 0 N.A. N.A. 0 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 54 0 0 0 14 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 7 0 0 0 54 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 14 0 7 7 0 0 7 7 0 0 7 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 7 20 0 % F
% Gly: 0 7 0 0 0 0 7 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 14 0 0 0 7 0 7 % I
% Lys: 47 34 7 34 40 0 0 7 0 0 54 20 0 0 7 % K
% Leu: 7 0 0 7 20 14 0 0 14 27 0 7 54 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 14 14 0 0 7 0 0 40 0 0 0 % N
% Pro: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 27 0 0 0 0 0 7 14 0 0 14 0 % Q
% Arg: 7 27 0 7 0 0 0 0 0 0 7 0 0 54 67 % R
% Ser: 0 0 0 7 0 0 20 20 14 0 0 0 0 0 0 % S
% Thr: 0 7 20 0 0 0 34 0 0 40 7 14 0 0 0 % T
% Val: 0 0 0 7 0 0 0 0 34 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _