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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HUNK All Species: 26.06
Human Site: Y153 Identified Species: 40.95
UniProt: P57058 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57058 NP_055401.1 714 79686 Y153 G N L M H K I Y E K K R L E E
Chimpanzee Pan troglodytes Q68UT7 714 79665 Y153 G N L M H K I Y E K K R L E E
Rhesus Macaque Macaca mulatta XP_001115547 734 82154 V142 G E V F D Y L V A H G R M K E
Dog Lupus familis XP_544857 756 84391 Y195 G N L M H K I Y E K K R L E E
Cat Felis silvestris
Mouse Mus musculus O88866 714 79585 Y153 G N L M H K I Y E K K R L D E
Rat Rattus norvegicus O08679 722 80853 V142 G E V F D Y L V A H G R M K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513072 722 82227 Y156 G D L L D R I Y N K Q K L E E
Chicken Gallus gallus Q9IA88 798 88848 T115 G E M F D H L T S N G H L S E
Frog Xenopus laevis Q5XHI9 691 78470 Y146 G N L M H K I Y E K K R L E E
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 V148 G E I F D H L V A H G R M A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 V259 G E V F D Y L V A H G R M K E
Sea Urchin Strong. purpuratus XP_794043 962 106011 C155 G P L L D R V C E K G G L E E
Poplar Tree Populus trichocarpa XP_002306053 515 59069 V12 S Y R G S S S V D M Y L A N Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 G9 D H S S N R F G N N G V E S I
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 Y119 H P H I I K L Y D V I K S K D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 26.1 78.5 N.A. 92.4 24.6 N.A. 35.7 26.6 64.5 23.4 N.A. N.A. N.A. 21.5 30
Protein Similarity: 100 99.8 46.4 83 N.A. 95.9 44.7 N.A. 54.5 43.3 76.8 36.6 N.A. N.A. N.A. 34.5 45.2
P-Site Identity: 100 100 20 100 N.A. 93.3 20 N.A. 53.3 20 100 20 N.A. N.A. N.A. 20 46.6
P-Site Similarity: 100 100 46.6 100 N.A. 100 46.6 N.A. 86.6 33.3 100 40 N.A. N.A. N.A. 46.6 66.6
Percent
Protein Identity: 26.3 N.A. N.A. 25.9 24.9 N.A.
Protein Similarity: 43.2 N.A. N.A. 43.2 42.7 N.A.
P-Site Identity: 0 N.A. N.A. 0 13.3 N.A.
P-Site Similarity: 6.6 N.A. N.A. 20 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 27 0 0 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 0 47 0 0 0 14 0 0 0 0 7 7 % D
% Glu: 0 34 0 0 0 0 0 0 40 0 0 0 7 40 80 % E
% Phe: 0 0 0 34 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 80 0 0 7 0 0 0 7 0 0 47 7 0 0 0 % G
% His: 7 7 7 0 34 14 0 0 0 27 0 7 0 0 0 % H
% Ile: 0 0 7 7 7 0 40 0 0 0 7 0 0 0 7 % I
% Lys: 0 0 0 0 0 40 0 0 0 47 34 14 0 27 0 % K
% Leu: 0 0 47 14 0 0 40 0 0 0 0 7 54 0 0 % L
% Met: 0 0 7 34 0 0 0 0 0 7 0 0 27 0 0 % M
% Asn: 0 34 0 0 7 0 0 0 14 14 0 0 0 7 0 % N
% Pro: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 7 0 0 20 0 0 0 0 0 60 0 0 0 % R
% Ser: 7 0 7 7 7 7 7 0 7 0 0 0 7 14 0 % S
% Thr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % T
% Val: 0 0 20 0 0 0 7 34 0 7 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 20 0 47 0 0 7 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _