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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUNK
All Species:
20.3
Human Site:
Y357
Identified Species:
31.9
UniProt:
P57058
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57058
NP_055401.1
714
79686
Y357
H
M
T
E
K
L
G
Y
K
N
S
D
V
I
N
Chimpanzee
Pan troglodytes
Q68UT7
714
79665
Y357
H
M
T
E
K
L
G
Y
K
N
S
D
V
I
N
Rhesus Macaque
Macaca mulatta
XP_001115547
734
82154
Y337
E
L
M
V
S
M
G
Y
T
R
E
E
I
Q
D
Dog
Lupus familis
XP_544857
756
84391
Y399
H
M
T
E
K
L
G
Y
K
N
S
D
V
I
N
Cat
Felis silvestris
Mouse
Mus musculus
O88866
714
79585
Y357
H
M
T
E
K
L
G
Y
K
N
S
D
V
I
N
Rat
Rattus norvegicus
O08679
722
80853
E341
S
M
G
Y
T
R
E
E
I
Q
D
S
L
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513072
722
82227
L361
Y
M
A
D
T
M
E
L
S
H
T
E
I
I
S
Chicken
Gallus gallus
Q9IA88
798
88848
I316
G
I
M
Q
T
L
G
I
D
R
Q
R
T
V
E
Frog
Xenopus laevis
Q5XHI9
691
78470
Y348
H
M
S
E
K
L
G
Y
K
H
S
D
V
I
N
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
I415
T
V
P
Q
V
Q
L
I
N
P
E
N
Q
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
N458
Q
I
F
Q
L
G
F
N
K
A
A
I
L
E
S
Sea Urchin
Strong. purpuratus
XP_794043
962
106011
I376
Y
I
R
E
T
L
G
I
K
S
T
H
V
S
E
Poplar Tree
Populus trichocarpa
XP_002306053
515
59069
P185
G
S
P
N
Y
A
A
P
E
V
I
S
G
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
N182
K
T
S
C
G
S
P
N
Y
A
A
P
E
V
I
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
I297
N
P
L
N
R
I
S
I
H
E
I
M
Q
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
26.1
78.5
N.A.
92.4
24.6
N.A.
35.7
26.6
64.5
23.4
N.A.
N.A.
N.A.
21.5
30
Protein Similarity:
100
99.8
46.4
83
N.A.
95.9
44.7
N.A.
54.5
43.3
76.8
36.6
N.A.
N.A.
N.A.
34.5
45.2
P-Site Identity:
100
100
13.3
100
N.A.
100
6.6
N.A.
13.3
13.3
86.6
6.6
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
100
100
46.6
100
N.A.
100
20
N.A.
66.6
33.3
100
26.6
N.A.
N.A.
N.A.
40
60
Percent
Protein Identity:
26.3
N.A.
N.A.
25.9
24.9
N.A.
Protein Similarity:
43.2
N.A.
N.A.
43.2
42.7
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
7
0
0
14
14
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
7
0
7
34
0
7
14
% D
% Glu:
7
0
0
40
0
0
14
7
7
7
14
14
7
7
14
% E
% Phe:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
7
0
7
7
54
0
0
0
0
0
7
0
7
% G
% His:
34
0
0
0
0
0
0
0
7
14
0
7
0
0
0
% H
% Ile:
0
20
0
0
0
7
0
27
7
0
14
7
14
47
7
% I
% Lys:
7
0
0
0
34
0
0
0
47
0
0
0
0
7
0
% K
% Leu:
0
7
7
0
7
47
7
7
0
0
0
0
14
0
7
% L
% Met:
0
47
14
0
0
14
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
14
0
0
0
14
7
27
0
7
0
0
34
% N
% Pro:
0
7
14
0
0
0
7
7
0
7
0
7
0
0
0
% P
% Gln:
7
0
0
20
0
7
0
0
0
7
7
0
14
7
0
% Q
% Arg:
0
0
7
0
7
7
0
0
0
14
0
7
0
0
0
% R
% Ser:
7
7
14
0
7
7
7
0
7
7
34
14
0
7
14
% S
% Thr:
7
7
27
0
27
0
0
0
7
0
14
0
7
0
0
% T
% Val:
0
7
0
7
7
0
0
0
0
7
0
0
40
20
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
7
7
0
0
40
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _