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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUNK
All Species:
24.24
Human Site:
Y388
Identified Species:
38.1
UniProt:
P57058
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57058
NP_055401.1
714
79686
Y388
L
N
K
K
L
E
R
Y
L
S
G
K
S
D
I
Chimpanzee
Pan troglodytes
Q68UT7
714
79665
Y388
L
N
K
K
L
E
R
Y
L
S
G
K
S
D
I
Rhesus Macaque
Macaca mulatta
XP_001115547
734
82154
V368
L
G
Y
K
S
S
E
V
Y
G
S
R
S
S
A
Dog
Lupus familis
XP_544857
756
84391
Y430
L
N
K
K
L
E
R
Y
L
S
G
K
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
O88866
714
79585
Y388
L
N
K
K
L
E
R
Y
L
S
G
K
S
D
I
Rat
Rattus norvegicus
O08679
722
80853
T372
S
S
E
L
E
G
D
T
I
T
L
K
P
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513072
722
82227
Y392
L
L
K
K
L
A
K
Y
H
K
E
Q
K
F
T
Chicken
Gallus gallus
Q9IA88
798
88848
Y347
L
L
E
R
L
K
E
Y
R
S
S
Q
L
S
S
Frog
Xenopus laevis
Q5XHI9
691
78470
Y379
L
N
R
K
L
E
H
Y
L
V
N
M
R
K
P
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Y446
S
P
E
A
M
A
R
Y
L
S
M
R
R
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
D489
G
E
R
K
S
D
M
D
A
S
E
I
T
M
A
Sea Urchin
Strong. purpuratus
XP_794043
962
106011
D407
L
A
K
Q
R
E
R
D
E
V
P
K
I
A
Q
Poplar Tree
Populus trichocarpa
XP_002306053
515
59069
P216
A
L
L
C
G
T
L
P
F
D
D
E
N
I
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
C213
V
I
L
Y
A
L
L
C
G
T
L
P
F
D
D
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
E328
P
H
P
E
E
E
N
E
N
N
D
S
K
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
26.1
78.5
N.A.
92.4
24.6
N.A.
35.7
26.6
64.5
23.4
N.A.
N.A.
N.A.
21.5
30
Protein Similarity:
100
99.8
46.4
83
N.A.
95.9
44.7
N.A.
54.5
43.3
76.8
36.6
N.A.
N.A.
N.A.
34.5
45.2
P-Site Identity:
100
100
20
100
N.A.
100
6.6
N.A.
33.3
26.6
46.6
26.6
N.A.
N.A.
N.A.
13.3
33.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
33.3
N.A.
46.6
53.3
53.3
46.6
N.A.
N.A.
N.A.
33.3
40
Percent
Protein Identity:
26.3
N.A.
N.A.
25.9
24.9
N.A.
Protein Similarity:
43.2
N.A.
N.A.
43.2
42.7
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
7
14
0
0
7
0
0
0
0
7
14
% A
% Cys:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
14
0
7
14
0
0
34
14
% D
% Glu:
0
7
20
7
14
47
14
7
7
0
14
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
7
7
0
% F
% Gly:
7
7
0
0
7
7
0
0
7
7
27
0
0
0
0
% G
% His:
0
7
0
0
0
0
7
0
7
0
0
0
0
7
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
0
0
7
7
7
27
% I
% Lys:
0
0
40
54
0
7
7
0
0
7
0
40
14
14
0
% K
% Leu:
60
20
14
7
47
7
14
0
40
0
14
0
7
0
0
% L
% Met:
0
0
0
0
7
0
7
0
0
0
7
7
0
7
0
% M
% Asn:
0
34
0
0
0
0
7
0
7
7
7
0
7
0
0
% N
% Pro:
7
7
7
0
0
0
0
7
0
0
7
7
7
0
20
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
14
0
0
7
% Q
% Arg:
0
0
14
7
7
0
40
0
7
0
0
14
14
7
0
% R
% Ser:
14
7
0
0
14
7
0
0
0
47
14
7
34
14
7
% S
% Thr:
0
0
0
0
0
7
0
7
0
14
0
0
7
0
14
% T
% Val:
7
0
0
0
0
0
0
7
0
14
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
54
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _