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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RWDD2B
All Species:
9.39
Human Site:
S178
Identified Species:
22.96
UniProt:
P57060
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57060
NP_058636.1
319
36332
S178
S
S
S
P
T
T
G
S
T
V
Q
S
V
D
L
Chimpanzee
Pan troglodytes
XP_531413
319
36342
S178
S
S
S
P
T
T
G
S
T
V
Q
S
V
D
L
Rhesus Macaque
Macaca mulatta
XP_001102697
290
33018
F158
V
Q
S
V
D
L
I
F
T
R
L
W
I
Y
S
Dog
Lupus familis
XP_544840
538
59327
S397
T
I
P
P
A
P
G
S
T
F
Q
P
V
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99M03
290
32873
A157
T
A
Q
P
E
D
L
A
F
T
R
L
W
I
Y
Rat
Rattus norvegicus
NP_001094029
290
33337
T157
T
V
Q
P
V
D
L
T
F
T
R
L
W
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416692
292
33501
V158
A
V
R
S
E
D
V
V
F
T
R
L
W
I
Y
Frog
Xenopus laevis
NP_001088728
296
33673
E159
T
G
S
P
E
N
A
E
F
T
R
L
W
I
Y
Zebra Danio
Brachydanio rerio
NP_001068583
289
33214
R157
Q
P
K
T
T
F
T
R
L
W
I
Y
S
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783392
329
37162
S176
Q
G
N
V
K
E
Q
S
K
K
K
Q
Q
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
89
51.6
N.A.
74.6
78
N.A.
N.A.
58.9
54.2
49.2
N.A.
N.A.
N.A.
N.A.
34
Protein Similarity:
100
99.6
89.6
55.3
N.A.
80.8
84.3
N.A.
N.A.
71.1
68.6
65.5
N.A.
N.A.
N.A.
N.A.
52.8
P-Site Identity:
100
100
13.3
53.3
N.A.
6.6
6.6
N.A.
N.A.
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
60
N.A.
33.3
26.6
N.A.
N.A.
13.3
26.6
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
30
0
0
0
0
0
0
0
30
0
% D
% Glu:
0
0
0
0
30
10
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
40
10
0
0
0
0
0
% F
% Gly:
0
20
0
0
0
0
30
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
10
0
10
40
0
% I
% Lys:
0
0
10
0
10
0
0
0
10
10
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
20
0
10
0
10
40
0
0
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
60
0
10
0
0
0
0
0
10
0
10
0
% P
% Gln:
20
10
20
0
0
0
10
0
0
0
30
10
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
10
0
10
40
0
0
0
0
% R
% Ser:
20
20
40
10
0
0
0
40
0
0
0
20
10
0
20
% S
% Thr:
40
0
0
10
30
20
10
10
40
40
0
0
0
0
0
% T
% Val:
10
20
0
20
10
0
10
10
0
20
0
0
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
10
40
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _