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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RWDD2B
All Species:
4.55
Human Site:
Y25
Identified Species:
11.11
UniProt:
P57060
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57060
NP_058636.1
319
36332
Y25
G
A
T
A
Q
E
T
Y
T
C
P
K
M
I
E
Chimpanzee
Pan troglodytes
XP_531413
319
36342
Y25
G
A
T
A
Q
E
T
Y
T
C
P
K
M
I
E
Rhesus Macaque
Macaca mulatta
XP_001102697
290
33018
N25
A
S
M
F
P
G
E
N
E
L
I
V
N
D
Q
Dog
Lupus familis
XP_544840
538
59327
G236
P
C
S
Q
K
T
Q
G
S
S
T
E
G
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99M03
290
32873
N25
A
S
M
F
P
S
E
N
E
L
I
V
N
D
Q
Rat
Rattus norvegicus
NP_001094029
290
33337
N25
A
S
M
F
P
G
E
N
E
L
I
V
N
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416692
292
33501
E25
S
S
M
F
P
Y
E
E
E
F
T
V
T
D
Q
Frog
Xenopus laevis
NP_001088728
296
33673
E25
S
M
F
P
T
E
D
E
F
V
V
T
D
Q
V
Zebra Danio
Brachydanio rerio
NP_001068583
289
33214
E25
I
S
M
F
P
S
E
E
G
L
Q
V
D
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783392
329
37162
L32
P
G
D
G
E
F
C
L
D
D
P
S
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
89
51.6
N.A.
74.6
78
N.A.
N.A.
58.9
54.2
49.2
N.A.
N.A.
N.A.
N.A.
34
Protein Similarity:
100
99.6
89.6
55.3
N.A.
80.8
84.3
N.A.
N.A.
71.1
68.6
65.5
N.A.
N.A.
N.A.
N.A.
52.8
P-Site Identity:
100
100
0
0
N.A.
0
0
N.A.
N.A.
0
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
33.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
20
0
20
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
10
0
0
20
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
10
10
0
0
20
40
0
% D
% Glu:
0
0
0
0
10
30
50
30
40
0
0
10
0
10
20
% E
% Phe:
0
0
10
50
0
10
0
0
10
10
0
0
0
0
0
% F
% Gly:
20
10
0
10
0
20
0
10
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
30
0
0
20
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
20
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
40
0
0
0
10
0
% L
% Met:
0
10
50
0
0
0
0
0
0
0
0
0
20
0
0
% M
% Asn:
0
0
0
0
0
0
0
30
0
0
0
0
30
0
0
% N
% Pro:
20
0
0
10
50
0
0
0
0
0
30
0
0
0
0
% P
% Gln:
0
0
0
10
20
0
10
0
0
0
10
0
0
10
40
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
20
50
10
0
0
20
0
0
10
10
0
10
0
0
10
% S
% Thr:
0
0
20
0
10
10
20
0
20
0
20
10
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
50
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
20
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _