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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX8 All Species: 11.82
Human Site: S20 Identified Species: 26
UniProt: P57073 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57073 NP_055402.2 446 47314 S20 C S P S G T A S S M S H V E D
Chimpanzee Pan troglodytes Q9BG89 509 56105 P22 E K G L S G A P S P T M S E D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852224 462 48670 S20 C S P S G T A S S M S H V E D
Cat Felis silvestris
Mouse Mus musculus Q04886 464 49860 S20 C S P S G T A S S M S H V E D
Rat Rattus norvegicus O55170 466 50021 A28 R C L S P S S A P S L G P D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506094 508 56382 P22 E K G M S A A P S P T M S E D
Chicken Gallus gallus P57074 470 50811 T22 P C S P A G T T S S M S H V D
Frog Xenopus laevis Q6VVD7 459 50447 M21 P T G T A S S M S H V S D S D
Zebra Danio Brachydanio rerio Q6RVD7 245 26782
Tiger Blowfish Takifugu rubipres NP_001072112 462 50618 N23 P C S P S G T N S S M S Q D E
Fruit Fly Dros. melanogaster P40657 784 84853 S83 H S P A I Q S S G Y E N E H L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.1 N.A. 81.8 N.A. 81.6 47.6 N.A. 46.4 70.8 71 25.1 65.8 23.7 N.A. N.A. N.A.
Protein Similarity: 100 57.3 N.A. 83.7 N.A. 84.9 58.1 N.A. 58.2 78.3 80.6 34.7 74.4 33.7 N.A. N.A. N.A.
P-Site Identity: 100 26.6 N.A. 100 N.A. 100 6.6 N.A. 26.6 13.3 13.3 0 6.6 20 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 N.A. 100 N.A. 100 33.3 N.A. 33.3 20 40 0 26.6 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 19 10 46 10 0 0 0 0 0 0 0 % A
% Cys: 28 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 19 64 % D
% Glu: 19 0 0 0 0 0 0 0 0 0 10 0 10 46 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 28 0 28 28 0 0 10 0 0 10 0 0 10 % G
% His: 10 0 0 0 0 0 0 0 0 10 0 28 10 10 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 10 0 0 0 0 0 0 10 0 0 0 10 % L
% Met: 0 0 0 10 0 0 0 10 0 28 19 19 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % N
% Pro: 28 0 37 19 10 0 0 19 10 19 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 37 19 37 28 19 28 37 73 28 28 28 19 10 0 % S
% Thr: 0 10 0 10 0 28 19 10 0 0 19 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 28 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _