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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C21orf59 All Species: 33.33
Human Site: S205 Identified Species: 66.67
UniProt: P57076 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57076 NP_067077.1 290 33224 S205 L R R T K K L S D Y V G K N E
Chimpanzee Pan troglodytes XP_531427 484 53544 S399 L R R T K K L S D Y V G K N E
Rhesus Macaque Macaca mulatta XP_001095882 290 33146 S205 L R R T K K L S D Y V G K N E
Dog Lupus familis XP_848523 290 33220 S205 L R R T K T L S D Y V G K N E
Cat Felis silvestris
Mouse Mus musculus NP_080778 290 33172 S205 L R R T K K L S D Y V G K N E
Rat Rattus norvegicus NP_001008289 290 33225 S205 L R R T K K L S D Y V G K N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006258 290 33033 S205 L K E T K L L S D Y V G R N E
Frog Xenopus laevis NP_001086851 290 33316 S205 L H R K Q K L S D Y V G K N E
Zebra Danio Brachydanio rerio Q6DRC3 290 33522 Q205 L H R G K K L Q D Y I G K N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZH1 291 33099 S205 M L M G K L M S D Y L G H N D
Honey Bee Apis mellifera XP_623297 290 33633 K205 M I I G K K L K D Y L G M N E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784987 290 32623 C205 M H R G K K L C D Y V G K N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 98.9 91.3 N.A. 92.4 91 N.A. N.A. 77.9 73 72.7 N.A. 49.1 62 N.A. 63.4
Protein Similarity: 100 56.6 99.6 96.9 N.A. 96.9 96.2 N.A. N.A. 89.3 86.5 85.1 N.A. 71.8 77.9 N.A. 78.9
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 73.3 80 73.3 N.A. 40 53.3 N.A. 73.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 86.6 86.6 80 N.A. 66.6 66.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 9 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 92 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 34 0 0 0 0 0 0 0 100 0 0 0 % G
% His: 0 25 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 9 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 9 0 9 92 75 0 9 0 0 0 0 75 0 0 % K
% Leu: 75 9 0 0 0 17 92 0 0 0 17 0 0 0 0 % L
% Met: 25 0 9 0 0 0 9 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 50 75 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 59 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _