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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAK1L All Species: 5.76
Human Site: S121 Identified Species: 14.07
UniProt: P57077 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57077 NP_064537.1 242 27248 S121 V P V E I P S S P L D D T P P
Chimpanzee Pan troglodytes XP_001161220 242 27141 S121 V P V E I P S S P L D D T P P
Rhesus Macaque Macaca mulatta XP_001103166 214 23942 Q113 L E F P E L D Q Q L Q P L P P
Dog Lupus familis XP_851430 287 31436 N166 R I A F S L D N A S D D T P P
Cat Felis silvestris
Mouse Mus musculus P58500 142 16253 L46 L E Q Q L Q P L P P C H D S V
Rat Rattus norvegicus P0C8E4 606 67182 S371 G R L S L G A S R G S S V E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507638 595 66386 A166 K I C D F G T A C D I Q T H M
Chicken Gallus gallus XP_416695 161 18322 P66 D Q Q L Q P L P P C H D S Q E
Frog Xenopus laevis NP_001084359 616 68446 A168 K I C D F G T A C D I Q T H M
Zebra Danio Brachydanio rerio NP_001018586 544 61104 A161 K I C D F G T A C D I Q T H M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 59 48 N.A. 48.3 21.6 N.A. 21.8 47.5 22.2 22.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 66.5 59.2 N.A. 55.7 30.6 N.A. 31 58.6 30.6 34.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 20 33.3 N.A. 6.6 6.6 N.A. 6.6 20 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 40 N.A. 26.6 26.6 N.A. 26.6 26.6 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 30 10 0 0 0 0 0 0 % A
% Cys: 0 0 30 0 0 0 0 0 30 10 10 0 0 0 0 % C
% Asp: 10 0 0 30 0 0 20 0 0 30 30 40 10 0 0 % D
% Glu: 0 20 0 20 10 0 0 0 0 0 0 0 0 10 10 % E
% Phe: 0 0 10 10 30 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 40 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 10 0 30 0 % H
% Ile: 0 40 0 0 20 0 0 0 0 0 30 0 0 0 0 % I
% Lys: 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 20 0 10 10 20 20 10 10 0 30 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 20 0 10 0 30 10 10 40 10 0 10 0 40 40 % P
% Gln: 0 10 20 10 10 10 0 10 10 0 10 30 0 10 0 % Q
% Arg: 10 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 10 0 20 30 0 10 10 10 10 10 10 % S
% Thr: 0 0 0 0 0 0 30 0 0 0 0 0 60 0 0 % T
% Val: 20 0 20 0 0 0 0 0 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _