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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
13.03
Human Site:
S391
Identified Species:
20.48
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S391
E
K
K
Q
R
R
R
S
P
P
P
G
P
D
G
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S391
E
K
K
Q
R
R
R
S
P
P
P
G
P
N
G
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S390
E
K
K
Q
R
R
R
S
P
P
P
G
P
N
G
Dog
Lupus familis
XP_544908
406
45137
P386
L
Q
K
R
R
Q
N
P
P
P
G
P
N
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
S392
L
K
K
K
R
Q
R
S
P
F
P
G
S
P
E
Rat
Rattus norvegicus
NP_001129139
365
40341
L348
H
L
R
E
S
W
A
L
L
V
Q
M
M
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
N475
E
R
K
K
T
K
R
N
P
H
P
G
A
N
G
Chicken
Gallus gallus
XP_416749
417
46882
N398
K
Q
K
K
K
R
Q
N
L
Q
H
D
A
N
G
Frog
Xenopus laevis
Q7ZY78
396
43627
K379
R
L
E
S
E
K
R
K
A
A
D
G
Q
V
V
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
A392
H
K
K
R
A
A
A
A
N
G
S
K
P
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
N403
W
F
K
K
R
F
D
N
V
S
D
Y
L
E
R
Honey Bee
Apis mellifera
XP_001120270
256
29743
Y239
S
I
L
Y
K
R
K
Y
D
N
I
Q
E
Y
L
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
L371
I
E
K
K
K
R
R
L
N
E
D
I
N
G
D
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
E417
M
L
D
E
E
D
D
E
E
G
E
E
E
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
E426
N
L
V
T
K
K
E
E
I
Y
P
L
Y
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
93.3
93.3
26.6
N.A.
53.3
0
N.A.
46.6
20
13.3
20
N.A.
13.3
6.6
20
0
P-Site Similarity:
100
100
100
46.6
N.A.
66.6
13.3
N.A.
80
66.6
26.6
40
N.A.
33.3
20
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
14
7
7
7
0
0
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
7
14
0
7
0
20
7
0
7
14
% D
% Glu:
27
7
7
14
14
0
7
14
7
7
7
7
14
7
7
% E
% Phe:
0
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
14
7
40
0
14
34
% G
% His:
14
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
7
7
0
0
0
0
0
0
7
0
7
7
0
0
0
% I
% Lys:
7
34
67
34
27
20
7
7
0
0
0
7
0
0
7
% K
% Leu:
14
27
7
0
0
0
0
14
14
0
0
7
7
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% M
% Asn:
7
0
0
0
0
0
7
20
14
7
0
0
14
40
0
% N
% Pro:
0
0
0
0
0
0
0
7
40
27
40
7
27
7
0
% P
% Gln:
0
14
0
20
0
14
7
0
0
7
7
7
7
0
7
% Q
% Arg:
7
7
7
14
40
40
47
0
0
0
0
0
0
0
7
% R
% Ser:
7
0
0
7
7
0
0
27
0
7
7
0
7
0
7
% S
% Thr:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
7
7
0
0
0
14
14
% V
% Trp:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
0
7
0
7
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _