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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR4 All Species: 28.48
Human Site: S97 Identified Species: 44.76
UniProt: P57081 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57081 NP_061139.2 412 45490 S97 T K P W Q C L S V R T V A R R
Chimpanzee Pan troglodytes XP_514923 412 45566 S97 T K P W Q C L S V R T V A R R
Rhesus Macaque Macaca mulatta XP_001105050 411 45737 S97 T K P W Q C L S V R T V A R R
Dog Lupus familis XP_544908 406 45137 S97 T K P W Q C L S V R T V V R R
Cat Felis silvestris
Mouse Mus musculus Q9EP82 413 45737 S99 T K P W Q C L S V R M V V R R
Rat Rattus norvegicus NP_001129139 365 40341 S69 G S D T I L A S T F S K S G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511691 493 54884 S181 Q P S W E C L S V R A V V R R
Chicken Gallus gallus XP_416749 417 46882 S107 K P S W E C I S I R P V N R R
Frog Xenopus laevis Q7ZY78 396 43627 R97 I S V R W V S R R C T A L T F
Zebra Danio Brachydanio rerio A4IGH4 413 46222 S98 E P S W K C I S T R W V V R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W415 424 46480 V104 T S T S V Q N V A Y S P D G Q
Honey Bee Apis mellifera XP_001120270 256 29743
Nematode Worm Caenorhab. elegans Q23232 388 43620 F92 N E K Q I H V F E Y F V N D K
Sea Urchin Strong. purpuratus XP_001202437 434 48995 S131 T L I L G H V S M L L D V V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03774 444 50470 N107 P I Y S Y I R N L R L T S D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 91.5 79.1 N.A. 75.3 64.8 N.A. 56.1 56.3 48.2 44.3 N.A. 27.8 24.7 25.7 32.4
Protein Similarity: 100 99.2 94.4 86.4 N.A. 83.2 74 N.A. 67.5 72.4 63.5 61 N.A. 44 38.1 42.2 52.7
P-Site Identity: 100 100 100 93.3 N.A. 86.6 13.3 N.A. 60 46.6 6.6 46.6 N.A. 6.6 0 6.6 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 26.6 N.A. 66.6 66.6 6.6 60 N.A. 20 0 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 7 0 7 7 20 0 0 % A
% Cys: 0 0 0 0 0 54 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 0 0 7 7 14 0 % D
% Glu: 7 7 0 0 14 0 0 0 7 0 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 0 7 7 0 0 0 7 % F
% Gly: 7 0 0 0 7 0 0 0 0 0 0 0 0 14 0 % G
% His: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 7 0 14 7 14 0 7 0 0 0 0 0 0 % I
% Lys: 7 34 7 0 7 0 0 0 0 0 0 7 0 0 7 % K
% Leu: 0 7 0 7 0 7 40 0 7 7 14 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 7 7 0 0 0 0 14 0 0 % N
% Pro: 7 20 34 0 0 0 0 0 0 0 7 7 0 0 0 % P
% Gln: 7 0 0 7 34 7 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 7 0 0 7 7 7 60 0 0 0 54 60 % R
% Ser: 0 20 20 14 0 0 7 67 0 0 14 0 14 0 0 % S
% Thr: 47 0 7 7 0 0 0 0 14 0 34 7 0 7 0 % T
% Val: 0 0 7 0 7 7 14 7 40 0 0 60 34 7 7 % V
% Trp: 0 0 0 54 7 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 7 0 7 0 0 0 0 14 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _