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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX4
All Species:
11.52
Human Site:
S285
Identified Species:
21.11
UniProt:
P57082
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57082
NP_060958.2
545
60204
S285
R
L
I
S
P
Q
L
S
A
T
P
D
V
G
P
Chimpanzee
Pan troglodytes
XP_001142886
544
60085
S284
R
L
I
S
P
Q
L
S
A
T
P
D
V
G
P
Rhesus Macaque
Macaca mulatta
XP_001110382
544
60001
S284
R
L
I
S
P
Q
L
S
A
T
P
D
V
G
P
Dog
Lupus familis
XP_548568
518
57556
R260
K
E
Y
P
V
V
P
R
S
T
V
R
Q
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P70325
552
61124
K292
V
S
S
Q
L
S
A
K
P
D
V
S
P
L
H
Rat
Rattus norvegicus
Q5I2P1
517
57726
R260
K
E
Y
P
V
V
P
R
S
T
V
R
H
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509128
544
60387
K284
V
S
T
Q
L
S
T
K
P
D
V
S
P
L
H
Chicken
Gallus gallus
Q9PWE8
521
58384
R264
V
V
P
R
S
T
V
R
Q
K
V
S
S
N
H
Frog
Xenopus laevis
Q9W7C2
519
58062
T262
Y
P
V
V
P
R
S
T
V
R
Q
K
V
S
S
Zebra Danio
Brachydanio rerio
Q9IAK8
492
55218
F235
N
N
P
F
A
K
G
F
R
G
S
D
D
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
A628
S
E
H
A
A
A
A
A
A
N
A
S
A
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
K166
G
A
N
F
H
K
L
K
L
T
N
N
I
S
D
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
T381
L
L
S
D
L
G
S
T
T
G
S
S
S
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.7
51.9
N.A.
92.2
51.9
N.A.
87.5
55
52.8
52.2
N.A.
24.4
N.A.
32.4
31
Protein Similarity:
100
99.4
98.7
63.2
N.A.
94.3
63.4
N.A.
91
66
64.9
62.5
N.A.
34.2
N.A.
48
45.7
P-Site Identity:
100
100
100
6.6
N.A.
0
6.6
N.A.
0
0
13.3
6.6
N.A.
6.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
20
N.A.
0
20
N.A.
0
13.3
33.3
13.3
N.A.
20
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
16
8
16
8
31
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
16
0
31
8
0
16
% D
% Glu:
0
24
0
0
0
0
0
0
0
0
0
0
0
8
16
% E
% Phe:
0
0
0
16
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
8
0
0
16
0
0
0
31
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
24
% H
% Ile:
0
0
24
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
16
0
0
0
0
16
0
24
0
8
0
8
0
16
0
% K
% Leu:
8
31
0
0
24
0
31
0
8
0
0
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
8
8
0
0
0
0
0
0
8
8
8
0
8
0
% N
% Pro:
0
8
16
16
31
0
16
0
16
0
24
0
16
0
24
% P
% Gln:
0
0
0
16
0
24
0
0
8
0
8
0
8
0
0
% Q
% Arg:
24
0
0
8
0
8
0
24
8
8
0
16
0
0
0
% R
% Ser:
8
16
16
24
8
16
16
24
16
0
16
39
16
16
8
% S
% Thr:
0
0
8
0
0
8
8
16
8
47
0
0
0
0
0
% T
% Val:
24
8
8
8
16
16
8
0
8
0
39
0
31
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _