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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX4
All Species:
20
Human Site:
S353
Identified Species:
36.67
UniProt:
P57082
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57082
NP_060958.2
545
60204
S353
L
D
L
P
C
K
R
S
Y
L
E
A
P
S
S
Chimpanzee
Pan troglodytes
XP_001142886
544
60085
S352
L
D
L
P
C
K
R
S
Y
L
E
A
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001110382
544
60001
S352
L
D
L
P
C
K
R
S
Y
L
E
A
P
S
S
Dog
Lupus familis
XP_548568
518
57556
D328
Y
H
C
T
K
R
K
D
E
E
C
S
T
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P70325
552
61124
S360
L
D
L
P
C
K
R
S
Y
L
E
T
P
S
S
Rat
Rattus norvegicus
Q5I2P1
517
57726
E328
H
C
T
K
R
K
D
E
E
C
S
S
T
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509128
544
60387
S352
L
D
L
P
C
K
R
S
Y
L
D
A
S
S
S
Chicken
Gallus gallus
Q9PWE8
521
58384
S332
K
R
K
D
E
E
C
S
T
T
E
H
P
Y
K
Frog
Xenopus laevis
Q9W7C2
519
58062
S330
H
C
T
K
R
K
V
S
E
E
P
A
E
H
S
Zebra Danio
Brachydanio rerio
Q9IAK8
492
55218
D303
S
V
S
S
T
S
Q
D
L
L
P
Q
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
G696
A
G
L
N
P
G
G
G
S
Y
P
S
P
N
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
N234
V
T
E
L
K
I
E
N
N
P
F
A
K
G
F
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
I449
S
G
S
G
L
G
A
I
D
G
G
V
N
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.7
51.9
N.A.
92.2
51.9
N.A.
87.5
55
52.8
52.2
N.A.
24.4
N.A.
32.4
31
Protein Similarity:
100
99.4
98.7
63.2
N.A.
94.3
63.4
N.A.
91
66
64.9
62.5
N.A.
34.2
N.A.
48
45.7
P-Site Identity:
100
100
100
0
N.A.
93.3
6.6
N.A.
86.6
20
26.6
20
N.A.
13.3
N.A.
6.6
0
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
13.3
N.A.
93.3
26.6
26.6
26.6
N.A.
26.6
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
47
0
8
0
% A
% Cys:
0
16
8
0
39
0
8
0
0
8
8
0
0
0
8
% C
% Asp:
0
39
0
8
0
0
8
16
8
0
8
0
0
0
0
% D
% Glu:
0
0
8
0
8
8
8
8
24
16
39
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
16
0
8
0
16
8
8
0
8
8
0
0
16
0
% G
% His:
16
8
0
0
0
0
0
0
0
0
0
8
0
8
8
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% I
% Lys:
8
0
8
16
16
54
8
0
0
0
0
0
8
0
8
% K
% Leu:
39
0
47
8
8
0
0
0
8
47
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
8
0
0
0
8
8
0
% N
% Pro:
0
0
0
39
8
0
0
0
0
8
24
0
47
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
16
8
39
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
16
8
0
8
0
54
8
0
8
24
16
47
54
% S
% Thr:
0
8
16
8
8
0
0
0
8
8
0
8
16
0
0
% T
% Val:
8
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
39
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _