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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX4 All Species: 20.3
Human Site: S360 Identified Species: 37.22
UniProt: P57082 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57082 NP_060958.2 545 60204 S360 S Y L E A P S S V G E D H Y F
Chimpanzee Pan troglodytes XP_001142886 544 60085 S359 S Y L E A P S S V G E D H Y F
Rhesus Macaque Macaca mulatta XP_001110382 544 60001 S359 S Y L E A P S S V G E D H Y F
Dog Lupus familis XP_548568 518 57556 E335 D E E C S T A E H P Y K K P Y
Cat Felis silvestris
Mouse Mus musculus P70325 552 61124 S367 S Y L E T P S S V G D D H Y F
Rat Rattus norvegicus Q5I2P1 517 57726 H335 E E C S S T E H P Y K K P Y M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509128 544 60387 S359 S Y L D A S S S V G D D H Y F
Chicken Gallus gallus Q9PWE8 521 58384 K339 S T T E H P Y K K P Y M E T S
Frog Xenopus laevis Q9W7C2 519 58062 S337 S E E P A E H S Y K K P Y M D
Zebra Danio Brachydanio rerio Q9IAK8 492 55218 S310 D L L P Q S S S Y H E H T Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 I703 G S Y P S P N I S V G P P I H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979 F241 N N P F A K G F R D A G A G K
Sea Urchin Strong. purpuratus XP_797010 645 70075 C456 I D G G V N G C D A R L S D Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.7 51.9 N.A. 92.2 51.9 N.A. 87.5 55 52.8 52.2 N.A. 24.4 N.A. 32.4 31
Protein Similarity: 100 99.4 98.7 63.2 N.A. 94.3 63.4 N.A. 91 66 64.9 62.5 N.A. 34.2 N.A. 48 45.7
P-Site Identity: 100 100 100 0 N.A. 86.6 6.6 N.A. 80 20 20 26.6 N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 100 100 20 N.A. 93.3 20 N.A. 93.3 20 33.3 26.6 N.A. 20 N.A. 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 47 0 8 0 0 8 8 0 8 0 0 % A
% Cys: 0 0 8 8 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 16 8 0 8 0 0 0 0 8 8 16 39 0 8 16 % D
% Glu: 8 24 16 39 0 8 8 8 0 0 31 0 8 0 0 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 39 % F
% Gly: 8 0 8 8 0 0 16 0 0 39 8 8 0 8 0 % G
% His: 0 0 0 0 8 0 8 8 8 8 0 8 39 0 8 % H
% Ile: 8 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 8 0 8 8 8 16 16 8 0 8 % K
% Leu: 0 8 47 0 0 0 0 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % M
% Asn: 8 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 24 0 47 0 0 8 16 0 16 16 8 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % R
% Ser: 54 8 0 8 24 16 47 54 8 0 0 0 8 0 8 % S
% Thr: 0 8 8 0 8 16 0 0 0 0 0 0 8 8 0 % T
% Val: 0 0 0 0 8 0 0 0 39 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 39 8 0 0 0 8 0 16 8 16 0 8 47 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _