KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX4
All Species:
20.91
Human Site:
S416
Identified Species:
38.33
UniProt:
P57082
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57082
NP_060958.2
545
60204
S416
D
L
P
P
P
P
L
S
C
N
M
W
T
S
V
Chimpanzee
Pan troglodytes
XP_001142886
544
60085
S415
D
L
P
P
P
P
L
S
C
N
M
W
T
S
V
Rhesus Macaque
Macaca mulatta
XP_001110382
544
60001
S415
D
L
P
P
P
P
L
S
C
N
M
W
T
S
V
Dog
Lupus familis
XP_548568
518
57556
P391
A
P
P
S
E
P
V
P
S
L
E
D
I
S
C
Cat
Felis silvestris
Mouse
Mus musculus
P70325
552
61124
S423
D
L
P
P
P
P
L
S
C
N
M
W
T
S
V
Rat
Rattus norvegicus
Q5I2P1
517
57726
S391
P
P
S
E
P
V
P
S
L
E
D
I
S
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509128
544
60387
S415
D
L
P
P
P
P
L
S
C
N
M
W
T
S
V
Chicken
Gallus gallus
Q9PWE8
521
58384
D395
D
P
V
P
S
L
E
D
I
S
C
N
T
W
P
Frog
Xenopus laevis
Q9W7C2
519
58062
V393
S
A
P
A
T
E
P
V
P
S
I
E
D
I
S
Zebra Danio
Brachydanio rerio
Q9IAK8
492
55218
G366
Q
S
L
G
L
S
G
G
A
P
Y
R
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
L759
L
F
N
A
Q
L
A
L
A
A
Q
H
P
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
P297
P
T
L
K
K
C
K
P
E
P
S
Q
T
P
T
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
S512
D
S
V
H
P
S
Y
S
A
R
S
M
T
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.7
51.9
N.A.
92.2
51.9
N.A.
87.5
55
52.8
52.2
N.A.
24.4
N.A.
32.4
31
Protein Similarity:
100
99.4
98.7
63.2
N.A.
94.3
63.4
N.A.
91
66
64.9
62.5
N.A.
34.2
N.A.
48
45.7
P-Site Identity:
100
100
100
20
N.A.
100
13.3
N.A.
100
20
6.6
0
N.A.
0
N.A.
6.6
26.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
20
N.A.
100
26.6
20
0
N.A.
13.3
N.A.
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
16
0
0
8
0
24
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
39
0
8
0
0
8
8
% C
% Asp:
54
0
0
0
0
0
0
8
0
0
8
8
8
0
0
% D
% Glu:
0
0
0
8
8
8
8
0
8
8
8
8
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
8
8
8
0
% I
% Lys:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
39
16
0
8
16
39
8
8
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
39
8
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
39
0
8
0
0
8
% N
% Pro:
16
24
54
47
54
47
16
16
8
16
0
0
16
8
8
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
8
16
8
8
8
16
0
54
8
16
16
0
8
47
16
% S
% Thr:
0
8
0
0
8
0
0
0
0
0
0
0
62
8
8
% T
% Val:
0
0
16
0
0
8
8
8
0
0
0
0
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
39
0
8
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _