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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX4
All Species:
18.79
Human Site:
S478
Identified Species:
34.44
UniProt:
P57082
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57082
NP_060958.2
545
60204
S478
F
S
V
Y
N
Q
L
S
Q
S
Q
V
R
E
R
Chimpanzee
Pan troglodytes
XP_001142886
544
60085
S477
F
S
V
Y
N
Q
L
S
Q
S
Q
V
R
E
R
Rhesus Macaque
Macaca mulatta
XP_001110382
544
60001
S477
F
S
V
Y
N
Q
L
S
Q
S
Q
V
R
E
R
Dog
Lupus familis
XP_548568
518
57556
G453
G
S
P
Q
L
G
E
G
M
F
Q
H
Q
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P70325
552
61124
S485
F
S
V
Y
N
Q
L
S
Q
S
Q
V
R
E
R
Rat
Rattus norvegicus
Q5I2P1
517
57726
M453
S
P
Q
L
G
E
G
M
F
Q
H
Q
T
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509128
544
60387
S477
F
S
V
Y
N
Q
I
S
Q
A
P
G
R
E
R
Chicken
Gallus gallus
Q9PWE8
521
58384
F457
I
G
D
T
H
S
M
F
Q
H
Q
T
S
V
S
Frog
Xenopus laevis
Q9W7C2
519
58062
H455
G
T
Q
P
S
D
S
H
S
M
F
Q
H
Q
S
Zebra Danio
Brachydanio rerio
Q9IAK8
492
55218
M428
A
H
F
A
S
R
Q
M
P
E
A
H
G
M
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
G821
R
S
G
D
P
P
G
G
G
G
G
G
L
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
M359
T
L
F
P
Q
F
S
M
A
L
N
S
P
A
A
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
S574
H
S
S
S
G
I
G
S
H
L
H
A
A
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.7
51.9
N.A.
92.2
51.9
N.A.
87.5
55
52.8
52.2
N.A.
24.4
N.A.
32.4
31
Protein Similarity:
100
99.4
98.7
63.2
N.A.
94.3
63.4
N.A.
91
66
64.9
62.5
N.A.
34.2
N.A.
48
45.7
P-Site Identity:
100
100
100
13.3
N.A.
100
0
N.A.
73.3
13.3
0
0
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
20
N.A.
100
6.6
N.A.
86.6
26.6
20
13.3
N.A.
6.6
N.A.
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
8
8
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
8
0
0
8
0
0
0
39
0
% E
% Phe:
39
0
16
0
0
8
0
8
8
8
8
0
0
0
0
% F
% Gly:
16
8
8
0
16
8
24
16
8
8
8
16
8
8
8
% G
% His:
8
8
0
0
8
0
0
8
8
8
16
16
8
0
0
% H
% Ile:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
8
0
31
0
0
16
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
8
24
8
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
39
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
8
16
8
8
0
0
8
0
8
0
8
0
0
% P
% Gln:
0
0
16
8
8
39
8
0
47
8
47
16
8
16
8
% Q
% Arg:
8
0
0
0
0
8
0
0
0
0
0
0
39
0
39
% R
% Ser:
8
62
8
8
16
8
16
47
8
31
0
8
8
16
24
% S
% Thr:
8
8
0
8
0
0
0
0
0
0
0
8
8
0
0
% T
% Val:
0
0
39
0
0
0
0
0
0
0
0
31
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _