KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX4
All Species:
21.82
Human Site:
S523
Identified Species:
40
UniProt:
P57082
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57082
NP_060958.2
545
60204
S523
F
L
Y
S
Q
T
F
S
L
S
R
E
S
S
L
Chimpanzee
Pan troglodytes
XP_001142886
544
60085
S522
F
L
Y
S
Q
T
F
S
L
S
R
E
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001110382
544
60001
S522
F
L
Y
S
Q
T
F
S
L
S
R
E
S
S
L
Dog
Lupus familis
XP_548568
518
57556
T496
Y
S
H
G
V
P
R
T
L
S
P
H
Q
Y
H
Cat
Felis silvestris
Mouse
Mus musculus
P70325
552
61124
S530
F
L
Y
S
Q
S
F
S
L
T
R
E
S
S
L
Rat
Rattus norvegicus
Q5I2P1
517
57726
L496
T
H
G
V
P
R
T
L
S
P
H
Q
Y
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509128
544
60387
S522
F
L
Y
S
Q
S
F
S
L
S
R
E
S
S
L
Chicken
Gallus gallus
Q9PWE8
521
58384
L500
S
H
G
V
P
R
T
L
S
P
H
Q
Y
H
S
Frog
Xenopus laevis
Q9W7C2
519
58062
I498
P
H
S
V
P
R
T
I
S
P
H
Q
Y
H
S
Zebra Danio
Brachydanio rerio
Q9IAK8
492
55218
L471
A
H
G
L
Q
R
T
L
S
P
H
Q
Y
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
V901
K
M
V
N
G
L
E
V
Q
H
N
G
S
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
E402
E
K
P
E
V
K
K
E
Q
K
S
V
T
P
P
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
S617
F
L
H
H
G
S
H
S
N
P
T
D
A
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.7
51.9
N.A.
92.2
51.9
N.A.
87.5
55
52.8
52.2
N.A.
24.4
N.A.
32.4
31
Protein Similarity:
100
99.4
98.7
63.2
N.A.
94.3
63.4
N.A.
91
66
64.9
62.5
N.A.
34.2
N.A.
48
45.7
P-Site Identity:
100
100
100
13.3
N.A.
86.6
0
N.A.
93.3
0
0
6.6
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
100
100
33.3
N.A.
100
6.6
N.A.
100
6.6
6.6
13.3
N.A.
26.6
N.A.
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
0
8
0
0
8
8
0
0
0
39
0
0
0
% E
% Phe:
47
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
24
8
16
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
31
16
8
0
0
8
0
0
8
31
8
0
31
8
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
0
8
8
0
0
8
0
0
0
0
0
% K
% Leu:
0
47
0
8
0
8
0
24
47
0
0
0
0
0
39
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
0
8
0
24
8
0
0
0
39
8
0
0
8
8
% P
% Gln:
0
0
0
0
47
0
0
0
16
0
0
31
8
0
0
% Q
% Arg:
0
0
0
0
0
31
8
0
0
0
39
0
0
0
0
% R
% Ser:
8
8
8
39
0
24
0
47
31
39
8
0
47
39
31
% S
% Thr:
8
0
0
0
0
24
31
8
0
8
8
0
8
0
8
% T
% Val:
0
0
8
24
16
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
39
0
0
0
0
0
0
0
0
0
31
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _