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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX4
All Species:
19.39
Human Site:
S529
Identified Species:
35.56
UniProt:
P57082
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57082
NP_060958.2
545
60204
S529
F
S
L
S
R
E
S
S
L
Q
Y
H
S
G
M
Chimpanzee
Pan troglodytes
XP_001142886
544
60085
S528
F
S
L
S
R
E
S
S
L
Q
Y
H
S
G
M
Rhesus Macaque
Macaca mulatta
XP_001110382
544
60001
S528
F
S
L
S
R
E
S
S
L
Q
Y
H
S
G
M
Dog
Lupus familis
XP_548568
518
57556
Y502
R
T
L
S
P
H
Q
Y
H
S
V
H
G
V
A
Cat
Felis silvestris
Mouse
Mus musculus
P70325
552
61124
S536
F
S
L
T
R
E
S
S
L
Q
Y
H
S
G
M
Rat
Rattus norvegicus
Q5I2P1
517
57726
H502
T
L
S
P
H
Q
Y
H
S
V
H
G
V
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509128
544
60387
S528
F
S
L
S
R
E
S
S
L
Q
Y
H
A
G
M
Chicken
Gallus gallus
Q9PWE8
521
58384
H506
T
L
S
P
H
Q
Y
H
S
V
H
G
V
G
M
Frog
Xenopus laevis
Q9W7C2
519
58062
H504
T
I
S
P
H
Q
Y
H
S
V
H
G
V
G
M
Zebra Danio
Brachydanio rerio
Q9IAK8
492
55218
H477
T
L
S
P
H
Q
Y
H
T
V
H
S
V
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
A907
E
V
Q
H
N
G
S
A
A
A
A
A
A
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
P408
K
E
Q
K
S
V
T
P
P
K
K
G
G
F
D
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
M623
H
S
N
P
T
D
A
M
S
M
N
M
N
M
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.7
51.9
N.A.
92.2
51.9
N.A.
87.5
55
52.8
52.2
N.A.
24.4
N.A.
32.4
31
Protein Similarity:
100
99.4
98.7
63.2
N.A.
94.3
63.4
N.A.
91
66
64.9
62.5
N.A.
34.2
N.A.
48
45.7
P-Site Identity:
100
100
100
20
N.A.
93.3
13.3
N.A.
93.3
13.3
13.3
0
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
26.6
N.A.
100
26.6
26.6
20
N.A.
26.6
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
8
8
8
8
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
8
0
0
0
39
0
0
0
0
0
0
0
0
0
% E
% Phe:
39
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
31
16
62
0
% G
% His:
8
0
0
8
31
8
0
31
8
0
31
47
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% K
% Leu:
0
24
47
0
0
0
0
0
39
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
8
0
8
62
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
39
8
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
0
31
8
0
0
39
0
0
0
0
0
% Q
% Arg:
8
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
47
31
39
8
0
47
39
31
8
0
8
31
8
0
% S
% Thr:
31
8
0
8
8
0
8
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
8
0
0
0
31
8
0
31
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
31
8
0
0
39
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _