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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX4 All Species: 21.21
Human Site: T323 Identified Species: 38.89
UniProt: P57082 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57082 NP_060958.2 545 60204 T323 P Q D L P L S T F P T Q R D S
Chimpanzee Pan troglodytes XP_001142886 544 60085 T322 P Q D L P L S T F P T Q R D S
Rhesus Macaque Macaca mulatta XP_001110382 544 60001 T322 P Q D L P L S T F P A Q R D S
Dog Lupus familis XP_548568 518 57556 S298 Y Q C E N G V S G P S Q D L L
Cat Felis silvestris
Mouse Mus musculus P70325 552 61124 T330 P Q D L P L N T F P T Q R D S
Rat Rattus norvegicus Q5I2P1 517 57726 G298 Q C E N G V S G P S Q D L L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509128 544 60387 T322 A Q D L P L N T F P A Q R D S
Chicken Gallus gallus Q9PWE8 521 58384 Q302 N G V S S T S Q D L L P P T N
Frog Xenopus laevis Q9W7C2 519 58062 T300 C E N G V S S T S Q D L L P S
Zebra Danio Brachydanio rerio Q9IAK8 492 55218 P273 R V G S S Q S P F S G D V Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 G666 S V G G S T G G A F R P T S T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979 S204 D R H N L M Y S T F R T F V F
Sea Urchin Strong. purpuratus XP_797010 645 70075 D419 H Q S D A M S D D L T K S R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.7 51.9 N.A. 92.2 51.9 N.A. 87.5 55 52.8 52.2 N.A. 24.4 N.A. 32.4 31
Protein Similarity: 100 99.4 98.7 63.2 N.A. 94.3 63.4 N.A. 91 66 64.9 62.5 N.A. 34.2 N.A. 48 45.7
P-Site Identity: 100 100 93.3 20 N.A. 93.3 6.6 N.A. 80 6.6 20 13.3 N.A. 0 N.A. 0 26.6
P-Site Similarity: 100 100 93.3 33.3 N.A. 100 20 N.A. 86.6 13.3 33.3 13.3 N.A. 6.6 N.A. 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 0 8 0 16 0 0 0 0 % A
% Cys: 8 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 39 8 0 0 0 8 16 0 8 16 8 39 0 % D
% Glu: 0 8 8 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 47 16 0 0 8 0 8 % F
% Gly: 0 8 16 16 8 8 8 16 8 0 8 0 0 0 8 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 0 0 39 8 39 0 0 0 16 8 8 16 16 8 % L
% Met: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 16 8 0 16 0 0 0 0 0 0 0 8 % N
% Pro: 31 0 0 0 39 0 0 8 8 47 0 16 8 8 8 % P
% Gln: 8 54 0 0 0 8 0 8 0 8 8 47 0 8 0 % Q
% Arg: 8 8 0 0 0 0 0 0 0 0 16 0 39 8 0 % R
% Ser: 8 0 8 16 24 8 62 16 8 16 8 0 8 8 54 % S
% Thr: 0 0 0 0 0 16 0 47 8 0 31 8 8 8 8 % T
% Val: 0 16 8 0 8 8 8 0 0 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _