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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX4 All Species: 19.7
Human Site: Y366 Identified Species: 36.11
UniProt: P57082 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57082 NP_060958.2 545 60204 Y366 S S V G E D H Y F R S P P P Y
Chimpanzee Pan troglodytes XP_001142886 544 60085 Y365 S S V G E D H Y F R S P P P Y
Rhesus Macaque Macaca mulatta XP_001110382 544 60001 Y365 S S V G E D H Y F R S P P P Y
Dog Lupus familis XP_548568 518 57556 P341 A E H P Y K K P Y M E T S P S
Cat Felis silvestris
Mouse Mus musculus P70325 552 61124 Y373 S S V G D D H Y F R S P P P Y
Rat Rattus norvegicus Q5I2P1 517 57726 Y341 E H P Y K K P Y M E T S P S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509128 544 60387 Y365 S S V G D D H Y F R S P P P Y
Chicken Gallus gallus Q9PWE8 521 58384 T345 Y K K P Y M E T S P A E E D P
Frog Xenopus laevis Q9W7C2 519 58062 M343 H S Y K K P Y M D T S P S E E
Zebra Danio Brachydanio rerio Q9IAK8 492 55218 Q316 S S Y H E H T Q D Y H C I K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 I709 N I S V G P P I H P S P H L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979 G247 G F R D A G A G K R E K K R Q
Sea Urchin Strong. purpuratus XP_797010 645 70075 D462 G C D A R L S D Y N T G N G M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.7 51.9 N.A. 92.2 51.9 N.A. 87.5 55 52.8 52.2 N.A. 24.4 N.A. 32.4 31
Protein Similarity: 100 99.4 98.7 63.2 N.A. 94.3 63.4 N.A. 91 66 64.9 62.5 N.A. 34.2 N.A. 48 45.7
P-Site Identity: 100 100 100 6.6 N.A. 93.3 13.3 N.A. 93.3 0 20 20 N.A. 13.3 N.A. 6.6 0
P-Site Similarity: 100 100 100 20 N.A. 100 26.6 N.A. 100 6.6 33.3 20 N.A. 20 N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 8 0 0 0 8 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 8 8 16 39 0 8 16 0 0 0 0 8 0 % D
% Glu: 8 8 0 0 31 0 8 0 0 8 16 8 8 8 16 % E
% Phe: 0 8 0 0 0 0 0 0 39 0 0 0 0 0 0 % F
% Gly: 16 0 0 39 8 8 0 8 0 0 0 8 0 8 0 % G
% His: 8 8 8 8 0 8 39 0 8 0 8 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 0 0 8 0 0 % I
% Lys: 0 8 8 8 16 16 8 0 8 0 0 8 8 8 0 % K
% Leu: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 8 0 8 8 8 0 0 0 0 8 % M
% Asn: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 8 16 0 16 16 8 0 16 0 54 47 47 8 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Q
% Arg: 0 0 8 0 8 0 0 0 0 47 0 0 0 8 8 % R
% Ser: 47 54 8 0 0 0 8 0 8 0 54 8 16 8 8 % S
% Thr: 0 0 0 0 0 0 8 8 0 8 16 8 0 0 0 % T
% Val: 0 0 39 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 16 8 16 0 8 47 16 8 0 0 0 0 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _