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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB25
All Species:
13.33
Human Site:
S184
Identified Species:
24.44
UniProt:
P57735
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57735
NP_065120.2
213
23496
S184
V
S
K
Q
R
Q
N
S
I
R
T
N
A
I
T
Chimpanzee
Pan troglodytes
XP_513873
206
22714
T180
Q
R
Q
N
S
I
R
T
N
A
I
T
L
G
S
Rhesus Macaque
Macaca mulatta
XP_001103732
304
33718
D271
V
S
Q
K
Q
M
S
D
R
R
E
N
D
M
S
Dog
Lupus familis
XP_547540
213
23354
S184
V
S
K
Q
R
Q
N
S
T
R
T
N
A
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTL2
213
23454
S184
V
S
K
Q
K
Q
N
S
T
R
T
S
A
I
T
Rat
Rattus norvegicus
P62494
216
24375
D183
V
S
Q
K
Q
M
S
D
R
R
E
N
D
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJN2
216
24420
D183
V
S
Q
K
Q
M
S
D
R
R
E
N
D
M
S
Frog
Xenopus laevis
NP_001086223
216
24179
I184
V
L
K
S
K
G
G
I
Q
Q
P
S
T
I
N
Zebra Danio
Brachydanio rerio
Q68EK7
213
23706
G186
D
P
E
R
M
G
S
G
I
Q
Y
G
D
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490675
211
23411
T183
V
S
N
K
H
V
G
T
D
R
Q
G
Y
G
G
Sea Urchin
Strong. purpuratus
NP_001116984
217
24438
D183
V
S
Q
K
N
I
R
D
G
G
N
G
E
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04486
217
24090
S184
I
S
K
K
S
I
S
S
D
Q
T
T
A
N
A
Baker's Yeast
Sacchar. cerevisiae
P38555
223
24451
L185
V
S
K
H
Q
M
D
L
G
D
S
S
A
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
44
91
N.A.
95.7
60.6
N.A.
N.A.
61.1
69.4
44.1
N.A.
N.A.
N.A.
60.5
59.9
Protein Similarity:
100
96.7
56.2
92.4
N.A.
98.5
77.7
N.A.
N.A.
78.2
82.8
60.5
N.A.
N.A.
N.A.
74.6
74.1
P-Site Identity:
100
0
26.6
86.6
N.A.
80
26.6
N.A.
N.A.
26.6
20
6.6
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
100
20
66.6
86.6
N.A.
93.3
66.6
N.A.
N.A.
66.6
40
40
N.A.
N.A.
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
52.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
74.1
68.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
39
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
31
16
8
0
0
31
8
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
24
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
16
16
8
16
8
0
24
0
16
16
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
24
0
8
16
0
8
0
0
31
0
% I
% Lys:
0
0
47
47
16
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
8
31
0
0
0
0
0
0
0
24
0
% M
% Asn:
0
0
8
8
8
0
24
0
8
0
8
39
0
16
8
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
39
24
31
24
0
0
8
24
8
0
0
0
0
% Q
% Arg:
0
8
0
8
16
0
16
0
24
54
0
0
0
0
0
% R
% Ser:
0
77
0
8
16
0
39
31
0
0
8
24
0
0
47
% S
% Thr:
0
0
0
0
0
0
0
16
16
0
31
16
8
0
16
% T
% Val:
77
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _