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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB25
All Species:
27.27
Human Site:
Y81
Identified Species:
50
UniProt:
P57735
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57735
NP_065120.2
213
23496
Y81
Y
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
Chimpanzee
Pan troglodytes
XP_513873
206
22714
V79
E
R
Y
Y
R
G
A
V
G
A
L
L
V
F
D
Rhesus Macaque
Macaca mulatta
XP_001103732
304
33718
Y168
Y
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
Dog
Lupus familis
XP_547540
213
23354
Y81
Y
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTL2
213
23454
Y81
Y
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
Rat
Rattus norvegicus
P62494
216
24375
Y81
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJN2
216
24420
Y81
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
L
Frog
Xenopus laevis
NP_001086223
216
24179
Y81
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
L
Zebra Danio
Brachydanio rerio
Q68EK7
213
23706
L85
Y
R
G
A
A
G
A
L
L
V
Y
D
I
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490675
211
23411
Y81
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
L
Sea Urchin
Strong. purpuratus
NP_001116984
217
24438
Y81
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04486
217
24090
Y81
Y
R
A
I
T
S
A
Y
Y
R
G
A
L
G
A
Baker's Yeast
Sacchar. cerevisiae
P38555
223
24451
Y82
Y
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
44
91
N.A.
95.7
60.6
N.A.
N.A.
61.1
69.4
44.1
N.A.
N.A.
N.A.
60.5
59.9
Protein Similarity:
100
96.7
56.2
92.4
N.A.
98.5
77.7
N.A.
N.A.
78.2
82.8
60.5
N.A.
N.A.
N.A.
74.6
74.1
P-Site Identity:
100
20
100
100
N.A.
100
6.6
N.A.
N.A.
6.6
6.6
20
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
N.A.
20
20
33.3
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
52.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
74.1
68.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
93.3
100
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
100
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
47
8
8
39
62
0
0
8
39
47
0
39
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
16
0
0
8
39
47
0
39
47
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
39
47
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
8
8
8
0
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
39
62
0
0
8
0
0
0
39
47
0
0
0
0
0
% R
% Ser:
0
0
0
0
39
47
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
39
47
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
8
0
39
47
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
8
8
0
0
39
85
47
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _