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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNX16
All Species:
31.21
Human Site:
S253
Identified Species:
68.67
UniProt:
P57768
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57768
NP_071416.2
344
39167
S253
E
K
Q
K
E
M
E
S
L
K
K
L
L
S
E
Chimpanzee
Pan troglodytes
XP_001168939
344
39118
S253
E
K
Q
K
E
M
E
S
L
K
K
L
L
S
E
Rhesus Macaque
Macaca mulatta
XP_001093964
344
39093
S253
E
K
Q
K
E
M
E
S
L
K
K
L
L
S
E
Dog
Lupus familis
XP_850210
344
39028
S253
E
K
Q
K
E
V
E
S
L
K
K
L
L
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C080
344
38785
S253
E
K
Q
K
E
V
E
S
L
K
K
L
L
G
E
Rat
Rattus norvegicus
P57769
344
38830
S253
E
K
Q
K
E
V
E
S
L
K
K
L
L
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507757
346
38949
S253
E
K
Q
R
E
V
E
S
L
K
K
L
L
N
E
Chicken
Gallus gallus
XP_418313
347
39150
S252
E
K
Q
R
E
V
E
S
L
K
K
L
L
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_991228
294
33214
E204
R
L
Q
K
E
L
L
E
K
Q
R
E
I
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393778
248
27766
V158
I
R
G
L
Q
A
F
V
N
G
I
L
S
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40959
511
59638
E406
M
A
A
N
N
V
V
E
L
Q
R
H
V
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.5
90.9
N.A.
83.7
84.8
N.A.
77.1
76.3
N.A.
53.2
N.A.
N.A.
29.3
N.A.
N.A.
Protein Similarity:
100
99.7
98.5
95.3
N.A.
90.9
92.1
N.A.
87.2
86.1
N.A.
64.2
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
80
86.6
N.A.
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
N.A.
53.3
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
73
0
0
0
82
0
73
19
0
0
0
10
0
10
73
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
73
0
64
0
0
0
0
10
73
73
0
0
0
0
% K
% Leu:
0
10
0
10
0
10
10
0
82
0
0
82
73
0
10
% L
% Met:
10
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
10
0
0
0
0
28
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
82
0
10
0
0
0
0
19
0
0
0
0
0
% Q
% Arg:
10
10
0
19
0
0
0
0
0
0
19
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
73
0
0
0
0
10
46
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
55
10
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _