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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS8
All Species:
36.36
Human Site:
S139
Identified Species:
80
UniProt:
P57771
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57771
NP_001095920.1
180
20917
S139
R
K
N
L
Q
E
P
S
L
T
C
F
D
Q
A
Chimpanzee
Pan troglodytes
XP_001161343
345
39468
S157
R
K
N
L
Q
E
P
S
L
T
C
F
D
Q
A
Rhesus Macaque
Macaca mulatta
XP_001114584
193
21754
T139
R
M
N
L
Q
T
V
T
A
T
C
F
D
T
A
Dog
Lupus familis
XP_547431
327
37363
S139
R
K
N
M
Q
E
P
S
L
T
C
F
D
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXT1
180
20945
S139
R
K
N
M
Q
E
P
S
L
T
C
F
D
Q
A
Rat
Rattus norvegicus
P49804
180
20931
S139
R
K
N
M
Q
E
P
S
L
T
C
F
D
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515953
180
20947
S139
R
K
N
M
Q
E
P
S
L
S
C
F
D
Q
A
Chicken
Gallus gallus
Q7SZC6
208
23504
T145
S
H
N
M
L
E
P
T
L
S
C
F
D
E
A
Frog
Xenopus laevis
A1A643
201
23280
T158
T
K
D
L
L
E
P
T
K
A
T
F
N
G
A
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
T129
K
N
R
L
L
E
P
T
P
H
S
L
N
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34295
201
23269
T124
N
T
N
M
S
R
P
T
Q
N
T
F
E
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
75.6
54.7
N.A.
98.3
98.8
N.A.
94.4
46.1
34.3
60.5
N.A.
N.A.
N.A.
32.8
N.A.
Protein Similarity:
100
51.8
80.8
55
N.A.
100
100
N.A.
97.2
64.9
56.2
77.2
N.A.
N.A.
N.A.
52.2
N.A.
P-Site Identity:
100
100
60
93.3
N.A.
93.3
93.3
N.A.
86.6
53.3
40
20
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
100
66.6
100
N.A.
100
100
N.A.
100
80
60
46.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
91
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
73
10
0
% D
% Glu:
0
0
0
0
0
82
0
0
0
0
0
0
10
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
64
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
46
28
0
0
0
64
0
0
10
0
0
0
% L
% Met:
0
10
0
55
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
82
0
0
0
0
0
0
10
0
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
91
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
64
0
0
0
10
0
0
0
0
55
0
% Q
% Arg:
64
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
0
55
0
19
10
0
0
0
0
% S
% Thr:
10
10
0
0
0
10
0
46
0
55
19
0
0
10
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _