KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEFSEC
All Species:
9.09
Human Site:
S67
Identified Species:
22.22
UniProt:
P57772
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57772
NP_068756.2
596
65305
S67
L
P
A
R
L
R
S
S
L
P
E
F
Q
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098682
596
65213
S67
L
P
A
R
L
R
S
S
L
P
E
F
Q
A
A
Dog
Lupus familis
XP_533720
600
65312
A67
L
P
A
R
L
R
P
A
L
P
A
P
P
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHW4
583
63398
S67
L
P
G
A
E
P
G
S
S
D
T
L
L
Q
V
Rat
Rattus norvegicus
NP_001102719
363
38887
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506507
511
56755
D32
I
G
G
A
Q
I
I
D
L
M
M
L
V
I
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085619
575
63305
T69
V
P
E
H
L
A
G
T
G
Y
Q
R
L
Q
F
Zebra Danio
Brachydanio rerio
NP_001032513
576
63216
S69
L
P
E
H
L
R
E
S
C
G
E
K
Q
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611584
511
56988
A32
S
S
I
S
S
T
A
A
F
D
K
N
P
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187129
849
93683
I181
E
G
A
A
R
E
V
I
N
R
I
Q
K
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
91.6
N.A.
87.7
56.7
N.A.
66.6
N.A.
70.4
63.4
N.A.
42.1
N.A.
N.A.
35.3
Protein Similarity:
100
N.A.
98.8
94.1
N.A.
91.1
57.8
N.A.
77.3
N.A.
82.2
76.5
N.A.
57.8
N.A.
N.A.
49
P-Site Identity:
100
N.A.
100
66.6
N.A.
20
0
N.A.
6.6
N.A.
13.3
46.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
73.3
N.A.
20
0
N.A.
13.3
N.A.
33.3
46.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
40
30
0
10
10
20
0
0
10
0
0
30
30
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
20
0
0
0
0
20
% D
% Glu:
10
0
20
0
10
10
10
0
0
0
30
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
20
0
0
10
% F
% Gly:
0
20
20
0
0
0
20
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
10
10
10
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% K
% Leu:
50
0
0
0
50
0
0
0
40
0
0
20
20
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
60
0
0
0
10
10
0
0
30
0
10
20
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
10
30
30
0
% Q
% Arg:
0
0
0
30
10
40
0
0
0
10
0
10
0
0
10
% R
% Ser:
10
10
0
10
10
0
20
40
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _