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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEFSEC
All Species:
20
Human Site:
Y373
Identified Species:
48.89
UniProt:
P57772
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57772
NP_068756.2
596
65305
Y373
S
F
N
F
S
Q
E
Y
L
F
Q
E
Q
Y
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098682
596
65213
Y373
S
F
D
F
S
Q
E
Y
L
F
Q
E
Q
Y
L
Dog
Lupus familis
XP_533720
600
65312
Y377
S
F
D
F
S
Q
E
Y
L
F
Q
E
Q
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHW4
583
63398
Y359
S
F
D
L
S
R
E
Y
L
F
Q
E
Q
Y
L
Rat
Rattus norvegicus
NP_001102719
363
38887
M149
R
Q
A
A
I
D
K
M
T
K
K
M
Q
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506507
511
56755
Q297
F
E
K
E
Y
L
Y
Q
E
E
Y
L
S
K
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085619
575
63305
Y361
A
F
D
F
G
K
E
Y
L
Y
Q
D
G
Y
I
Zebra Danio
Brachydanio rerio
NP_001032513
576
63216
T358
E
N
G
D
S
K
P
T
S
Q
E
Q
S
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611584
511
56988
Y297
Q
F
K
P
I
R
Y
Y
K
E
V
I
K
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187129
849
93683
E623
S
E
F
N
F
E
P
E
Y
L
Y
E
E
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
91.6
N.A.
87.7
56.7
N.A.
66.6
N.A.
70.4
63.4
N.A.
42.1
N.A.
N.A.
35.3
Protein Similarity:
100
N.A.
98.8
94.1
N.A.
91.1
57.8
N.A.
77.3
N.A.
82.2
76.5
N.A.
57.8
N.A.
N.A.
49
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
80
6.6
N.A.
0
N.A.
46.6
6.6
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
20
N.A.
0
N.A.
86.6
26.6
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
40
10
0
10
0
0
0
0
0
10
0
0
10
% D
% Glu:
10
20
0
10
0
10
50
10
10
20
10
50
10
10
0
% E
% Phe:
10
60
10
40
10
0
0
0
0
40
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
20
0
0
20
10
0
10
10
10
0
10
20
0
% K
% Leu:
0
0
0
10
0
10
0
0
50
10
0
10
0
0
50
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
10
% M
% Asn:
0
10
10
10
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
10
0
0
20
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
30
0
10
0
10
50
10
50
0
0
% Q
% Arg:
10
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
0
0
0
50
0
0
0
10
0
0
0
20
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
20
60
10
10
20
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _