KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEFSEC
All Species:
16.06
Human Site:
Y459
Identified Species:
39.26
UniProt:
P57772
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57772
NP_068756.2
596
65305
Y459
H
G
L
E
D
R
N
Y
A
D
S
F
L
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098682
596
65213
Y459
H
G
L
E
D
R
N
Y
A
D
S
F
L
P
R
Dog
Lupus familis
XP_533720
600
65312
Y463
H
G
L
E
G
K
D
Y
A
E
S
F
L
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHW4
583
63398
Y446
Q
G
L
E
D
K
N
Y
I
E
S
F
L
P
A
Rat
Rattus norvegicus
NP_001102719
363
38887
T228
K
G
Q
G
T
V
M
T
G
T
I
L
S
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506507
511
56755
M376
G
L
E
D
K
N
Y
M
E
T
F
L
P
K
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085619
575
63305
K440
L
L
E
G
V
E
D
K
N
Y
S
E
S
F
L
Zebra Danio
Brachydanio rerio
NP_001032513
576
63216
K440
L
L
E
G
F
E
D
K
N
Y
T
E
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611584
511
56988
A376
P
P
H
S
T
L
I
A
S
K
L
D
M
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187129
849
93683
Y711
H
A
I
T
D
K
N
Y
V
E
T
V
L
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
91.6
N.A.
87.7
56.7
N.A.
66.6
N.A.
70.4
63.4
N.A.
42.1
N.A.
N.A.
35.3
Protein Similarity:
100
N.A.
98.8
94.1
N.A.
91.1
57.8
N.A.
77.3
N.A.
82.2
76.5
N.A.
57.8
N.A.
N.A.
49
P-Site Identity:
100
N.A.
100
73.3
N.A.
66.6
6.6
N.A.
0
N.A.
6.6
0
N.A.
0
N.A.
N.A.
40
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
6.6
N.A.
6.6
N.A.
13.3
13.3
N.A.
13.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
30
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
40
0
30
0
0
20
0
10
0
10
0
% D
% Glu:
0
0
30
40
0
20
0
0
10
30
0
20
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
10
40
0
10
0
% F
% Gly:
10
50
0
30
10
0
0
0
10
0
0
0
0
10
0
% G
% His:
40
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
10
0
10
0
0
0
0
% I
% Lys:
10
0
0
0
10
30
0
20
0
10
0
0
0
10
0
% K
% Leu:
20
30
40
0
0
10
0
0
0
0
10
20
50
0
30
% L
% Met:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
10
40
0
20
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
0
0
10
50
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
30
% R
% Ser:
0
0
0
10
0
0
0
0
10
0
50
0
20
0
0
% S
% Thr:
0
0
0
10
20
0
0
10
0
20
20
0
10
0
10
% T
% Val:
0
0
0
0
10
10
0
0
10
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
50
0
20
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _