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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW4
All Species:
11.52
Human Site:
S18
Identified Species:
28.15
UniProt:
P57775
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57775
NP_071322.1
412
46337
S18
E
E
E
A
A
R
E
S
A
A
R
P
A
A
G
Chimpanzee
Pan troglodytes
XP_507994
575
62275
S173
E
E
E
A
A
R
E
S
A
A
R
P
A
A
G
Rhesus Macaque
Macaca mulatta
XP_001110869
410
46201
S16
E
E
E
A
A
R
E
S
A
A
R
P
A
A
G
Dog
Lupus familis
XP_543981
408
45636
P14
E
E
A
A
A
R
E
P
A
G
R
P
A
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMJ2
410
46123
P16
A
A
A
A
A
V
E
P
A
T
R
P
A
A
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511284
401
44487
S13
Q
C
L
A
Q
R
T
S
P
V
K
R
A
L
R
Chicken
Gallus gallus
XP_001233793
416
46314
A19
A
E
G
G
S
R
A
A
S
P
P
P
S
S
S
Frog
Xenopus laevis
NP_001091296
417
47291
L8
M
W
P
H
L
L
H
L
P
E
E
I
L
L
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122354
423
49394
T9
T
G
V
W
R
L
D
T
L
P
S
D
V
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196990
262
29395
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
98.3
94.9
N.A.
91
N.A.
N.A.
49
68.7
61.1
N.A.
N.A.
N.A.
30.5
N.A.
25.7
Protein Similarity:
100
68.6
98.7
95.8
N.A.
93.9
N.A.
N.A.
61.4
80.2
75.7
N.A.
N.A.
N.A.
46.5
N.A.
39.8
P-Site Identity:
100
100
100
80
N.A.
60
N.A.
N.A.
26.6
20
0
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
60
N.A.
N.A.
40
53.3
0
N.A.
N.A.
N.A.
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
20
60
50
0
10
10
50
30
0
0
60
50
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% D
% Glu:
40
50
30
0
0
0
50
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
0
0
0
0
0
10
0
0
0
0
50
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
10
0
10
20
0
10
10
0
0
0
10
30
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
20
20
20
10
60
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
60
0
0
0
0
50
10
0
0
10
% R
% Ser:
0
0
0
0
10
0
0
40
10
0
10
0
10
10
10
% S
% Thr:
10
0
0
0
0
0
10
10
0
10
0
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _