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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW4
All Species:
26.06
Human Site:
S288
Identified Species:
63.7
UniProt:
P57775
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57775
NP_071322.1
412
46337
S288
Q
L
M
T
H
L
G
S
D
F
P
P
G
A
G
Chimpanzee
Pan troglodytes
XP_507994
575
62275
S451
Q
L
M
T
H
L
G
S
D
F
P
P
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001110869
410
46201
S286
Q
L
M
T
H
L
G
S
D
F
P
P
G
A
G
Dog
Lupus familis
XP_543981
408
45636
S284
Q
L
M
M
H
L
G
S
D
F
P
P
G
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMJ2
410
46123
S286
Q
L
I
T
H
L
G
S
D
F
P
P
G
A
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511284
401
44487
G284
Q
G
A
V
I
V
S
G
S
R
D
R
T
A
K
Chicken
Gallus gallus
XP_001233793
416
46314
T293
Q
L
L
T
C
L
G
T
D
F
H
H
G
A
G
Frog
Xenopus laevis
NP_001091296
417
47291
T287
Q
L
M
T
C
L
G
T
D
F
R
R
G
A
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122354
423
49394
P274
T
E
S
D
I
L
K
P
D
K
R
R
C
A
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196990
262
29395
T146
K
V
W
D
I
G
T
T
Q
S
T
V
C
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
98.3
94.9
N.A.
91
N.A.
N.A.
49
68.7
61.1
N.A.
N.A.
N.A.
30.5
N.A.
25.7
Protein Similarity:
100
68.6
98.7
95.8
N.A.
93.9
N.A.
N.A.
61.4
80.2
75.7
N.A.
N.A.
N.A.
46.5
N.A.
39.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
13.3
66.6
73.3
N.A.
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
20
80
80
N.A.
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
90
0
% A
% Cys:
0
0
0
0
20
0
0
0
0
0
0
0
20
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
80
0
10
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
70
10
0
0
0
0
70
10
80
% G
% His:
0
0
0
0
50
0
0
0
0
0
10
10
0
0
0
% H
% Ile:
0
0
10
0
30
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% K
% Leu:
0
70
10
0
0
80
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
50
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
50
50
0
0
0
% P
% Gln:
80
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
20
30
0
0
0
% R
% Ser:
0
0
10
0
0
0
10
50
10
10
0
0
0
0
0
% S
% Thr:
10
0
0
60
0
0
10
30
0
0
10
0
10
0
0
% T
% Val:
0
10
0
10
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _