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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW4
All Species:
22.42
Human Site:
T223
Identified Species:
54.81
UniProt:
P57775
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57775
NP_071322.1
412
46337
T223
V
S
G
S
R
D
R
T
A
K
V
W
P
L
A
Chimpanzee
Pan troglodytes
XP_507994
575
62275
T386
V
S
G
S
R
D
R
T
A
K
V
W
P
L
A
Rhesus Macaque
Macaca mulatta
XP_001110869
410
46201
T221
V
S
G
S
R
D
R
T
A
K
V
W
P
L
A
Dog
Lupus familis
XP_543981
408
45636
T219
V
S
G
S
R
D
R
T
A
K
V
W
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMJ2
410
46123
T221
V
S
G
S
R
D
R
T
A
K
V
W
P
L
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511284
401
44487
R219
P
D
G
S
S
L
H
R
R
P
L
A
I
F
S
Chicken
Gallus gallus
XP_001233793
416
46314
T228
V
S
G
S
R
D
R
T
A
K
V
W
S
L
S
Frog
Xenopus laevis
NP_001091296
417
47291
D222
L
H
T
I
Q
T
D
D
R
V
W
S
V
A
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122354
423
49394
V209
S
G
S
S
D
G
T
V
K
I
W
G
P
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196990
262
29395
R81
L
T
S
V
D
A
T
R
E
L
I
I
A
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
98.3
94.9
N.A.
91
N.A.
N.A.
49
68.7
61.1
N.A.
N.A.
N.A.
30.5
N.A.
25.7
Protein Similarity:
100
68.6
98.7
95.8
N.A.
93.9
N.A.
N.A.
61.4
80.2
75.7
N.A.
N.A.
N.A.
46.5
N.A.
39.8
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
86.6
0
N.A.
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
26.6
93.3
13.3
N.A.
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
60
0
0
10
10
10
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
20
60
10
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
70
0
0
10
0
0
0
0
0
10
0
10
10
% G
% His:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
10
10
10
10
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
60
0
0
0
0
0
% K
% Leu:
20
0
0
0
0
10
0
0
0
10
10
0
0
60
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
0
0
60
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
60
0
60
20
20
0
0
0
0
0
0
% R
% Ser:
10
60
20
80
10
0
0
0
0
0
0
10
10
0
20
% S
% Thr:
0
10
10
0
0
10
20
60
0
0
0
0
0
0
10
% T
% Val:
60
0
0
10
0
0
0
10
0
10
60
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
20
60
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _